Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24642659 | 0.81 | NPC1 (0.59) | NPC1RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL26499469 | 0.81 | CTSL (0.46) | KMT2A | |
| SCHEMBL27710873 | 0.80 | NPC1 (0.58) | NPC1RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL10136058 | 0.80 | NPC1 (0.58) | NPC1RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL25975953 | 0.79 | NPC1 (0.47) | NPC1RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL22457527 | 0.79 | NPC1 (0.59) | NPC1RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL31633415 | 0.79 | NPC1 (0.59) | NPC1RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL25668395 | 0.78 | FAAH (0.44) | NPC1RAB9AKMT2ATAAR1MEN1 | |
| SCHEMBL25975345 | 0.77 | CHRNB2 (0.44) | — | |
| SCHEMBL10136051 | 0.75 | NPC1 (0.51) | NPC1RAB9AKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4227310-A1 | CAMPTOTHECIN DERIVATIVE AND LIGAND-DRUG CONJUGATE THEREOF | Sichuan Baili Pharmaceutical Co. Ltd. (CN) | 2023-08-16 | — | — | EP | disclosed |