Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 5/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31314669 | 1.00 | PTPN1 (0.42) | PTPN1RENKLK7KLK5PPARA | |
| SCHEMBL22703470 | 1.00 | PTPN1 (0.42) | PTPN1RENKLK7KLK5PPARA | |
| SCHEMBL31314662 | 0.92 | AAK1 (0.38) | PTPN1RENKLK7KLK5PPARA | |
| SCHEMBL23323441 | 0.90 | SYK (0.44) | PTPN1PPARAMAPTALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL31314675 | 0.87 | GHSR (0.42) | TACR3AAK1MRGPRX4 | |
| Hydrochloric Acid SCHEMBL31314670 | 0.84 | TACR3 (0.39) | TACR3MRGPRX4 | |
| SCHEMBL2996643 | 0.83 | POLB (0.51) | MAPTALDH1A1LMNAPKMHPGD | |
| SCHEMBL22703144 | 0.81 | PPARG (0.44) | PPARAMAPTNPSR1TACR3CTSS | |
| SCHEMBL22703156 | 0.81 | PPARG (0.44) | PPARAMAPTNPSR1TACR3CTSS | |
| SCHEMBL26045959 | 0.80 | MRGPRX4 (0.43) | PKMRAB9AMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151991-A1 | RNAI AGENTS FOR INHIBITING INFLUENZA A VIRAL GENE EXPRESSION, COMPOSITIONS THEREOF, AND METHODS OF USE | Arrowhead Pharmaceuticals, Inc. (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2023150622-A2 | RNAI AGENTS FOR INHIBITING EXPRESSION OF CORONAVIRUS (COV) VIRAL GENOMES, COMPOSITIONS THEREOF, AND METHODS OF USE | Arrowhead Pharmaceuticals, Inc. (US) | 2023-08-10 | — | — | WO | disclosed |
| WO-2023070082-A2 | RNAI AGENTS FOR INHIBITING EXPRESSION OF MATRIX METALLOPROTEINASE 7(MMP7), COMPOSITIONS THEREOF, AND METHODS OF USE | Arrowhead Pharmaceuticals, Inc. (US) | 2023-04-27 | — | — | WO | disclosed |