SCHEMBL25976558

SCHEMBL25976558

Cc1ccccc1-c1cc(-c2cc(-c3ccccc3)ccc2C)[n+](C)cc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 1/20 0.38
PLA2G7 Q13093 2/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
HTT P42858 2/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
APAF1 O14727 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
THRB P10828 1/20 0.36
XBP1 P17861 1/20 0.36
PTBP1 P26599 1/20 0.36
GALK1 P51570 1/20 0.36
BLM P54132 1/20 0.36
SMAD3 P84022 1/20 0.36
ATM Q13315 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25976919 0.91 AR (0.38) PLA2G7CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL25976556 0.91 HTT (0.36) SMN1; SMN2NPC1RAB9AHTTKMT2A
SCHEMBL25976597 0.89 RAB9A (0.39) SLC6A9SMN1; SMN2NPC1RAB9AHTT
SCHEMBL25976595 0.89 TYMS (0.36) SLC6A9SMN1; SMN2NPC1RAB9AHTT
SCHEMBL25976918 0.88 CA12 (0.40) KMT2AKDM4ECYP1A2CYP3A4CYP2C9
SCHEMBL25452197 0.86 HTT (0.37) SLC6A9SMN1; SMN2NPC1RAB9AHTT
SCHEMBL25976977 0.85 ESR2 (0.36) PLA2G7SMN1; SMN2NPC1RAB9AHTT
SCHEMBL25976656 0.85 ESR2 (0.36) PLA2G7SMN1; SMN2NPC1RAB9AHTT
SCHEMBL25976598 0.85 PSMB5 (0.35) SMN1; SMN2NPC1RAB9AHTTKMT2A
SCHEMBL25976921 0.83 TRPA1 (0.35) PLA2G7CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331758-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-11725021-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11725021-B2 Organic electroluminescent materials and devices NCL, OCIAD2, OCIAD1 SLC6A9 680/4885PLA2G7 3328/4885SMN1; SMN2 3169/4885
US-20230331758-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NCL, OCIAD2, OCIAD1 SLC6A9 680/4885PLA2G7 3328/4885SMN1; SMN2 3169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.