Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.68 |
| ▸ | DRD3 | P35462 | 1/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | PRKACG | P22612 | 1/20 | 0.49 |
| ▸ | PRKACB | P22694 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1825157 | 0.83 | DRD2 (0.53) | DRD2DRD3 | |
| SCHEMBL323312 | 0.81 | DRD3 (1.00) | DRD2DRD3HTR1APRKACAPRKACG | |
| SCHEMBL2296934 | 0.81 | DRD2 (0.68) | DRD2DRD3HTR1APRKACAPRKACG | |
| SCHEMBL28215396 | 0.81 | DRD2 (0.68) | DRD2DRD3HTR1APRKACAPRKACG | |
| SCHEMBL30752418 | 0.81 | DRD2 (0.68) | DRD2DRD3HTR1APRKACAPRKACG | |
| SCHEMBL2293961 | 0.81 | DRD2 (0.68) | DRD2DRD3HTR1APRKACAPRKACG | |
| Hydrochloric Acid SCHEMBL16463508 | 0.80 | DRD2 (0.66) | DRD2DRD3HTR1APRKACAPRKACG | |
| SCHEMBL16057462 | 0.80 | DRD2 (0.69) | DRD2DRD3HTR1APRKACAPRKACG | |
| SCHEMBL28705095 | 0.78 | DRD2 (0.46) | DRD2DRD3 | |
| SCHEMBL16517709 | 0.78 | DRD2 (0.46) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890820-B | Aminopyrazolopyrimidine compounds as neurotrophin tyrosine kinase receptor inhibitors | 正大天晴药业集团股份有限公司 | 2020-11-03 | — | — | CN | disclosed |
| CN-111163766-A | AHR inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2020-05-15 | — | — | CN | disclosed |
| EP-2571872-B1 | COMPOUNDS | TREHERNE JOHNATHAN MARK (GB) | 2014-12-31 | — | — | EP | disclosed |
| EP-2571872-A1 | COMPOUNDS | BTG International Limited (GB) | 2013-03-27 | — | — | EP | disclosed |
| EP-2571856-A1 | COMPOUNDS | BTG International Limited (GB) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011144578-A1 | COMPOUNDS | SENEXIS LIMITED (GB) | 2011-11-24 | — | — | WO | disclosed |
| WO-2011144577-A1 | COMPOUNDS | SENEXIS LIMITED (GB) | 2011-11-24 | — | — | WO | disclosed |