SCHEMBL28215396

SCHEMBL28215396

Fc1cccc(C2CNCCO2)c1

nearest known ligand 0.68

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.68
DRD3 P35462 1/20 0.68
HTR1A P08908 1/20 0.67
PRKACA P17612 1/20 0.51
PRKACG P22612 1/20 0.51
PRKACB P22694 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2296934 1.00 DRD2 (0.68) DRD2DRD3HTR1APRKACAPRKACG
SCHEMBL2293961 1.00 DRD2 (0.68) DRD2DRD3HTR1APRKACAPRKACG
SCHEMBL30752418 1.00 DRD2 (0.68) DRD2DRD3HTR1APRKACAPRKACG
Hydrochloric Acid SCHEMBL16463508 0.98 DRD2 (0.66) DRD2DRD3HTR1APRKACAPRKACG
SCHEMBL6225983 0.83 DRD2 (0.53) DRD2DRD3HTR1A
SCHEMBL16057462 0.82 DRD2 (0.69) DRD2DRD3HTR1APRKACAPRKACG
SCHEMBL2597678 0.81 DRD2 (0.68) DRD2DRD3HTR1APRKACAPRKACG
SCHEMBL11681496 0.81 DRD2 (0.68) DRD2DRD3HTR1APRKACAPRKACG
SCHEMBL22425357 0.81 DRD2 (0.68) DRD2DRD3HTR1APRKACAPRKACG
SCHEMBL6389994 0.81 DRD2 (0.68) DRD2DRD3HTR1APRKACAPRKACG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117402124-A Aryl sulfonamide compound and anti-influenza application thereof 中国医学科学院医药生物技术研究所 2024-01-16 CN disclosed
CN-107922431-A HPK1 inhibitors and methods of use thereof 大学健康网络 2018-04-17 CN disclosed