SCHEMBL25976884

SCHEMBL25976884

CCCCCCCCCCCCCCCCCOCC[C@H](COP(=O)(O)OC[C@@H]1CC[C@](C#N)(c2ccc3c(N)ncnn23)O1)OCc1ccc(C#N)cc1

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PLA2G10 O15496 2/20 0.32
▸ PLA2G1B P04054 2/20 0.32
▸ PLA2G2A P14555 2/20 0.32
▸ PLA2G5 P39877 2/20 0.32
▸ CYP3A4 P08684 1/20 0.30
▸ CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24304666 0.92 PLA2G10 (0.32) PLA2G10PLA2G1BPLA2G2APLA2G5
SCHEMBL25973653 0.91 RPS6KB1 (0.30) —
SCHEMBL25973634 0.91 PLA2G10 (0.31) PLA2G10PLA2G1BPLA2G2APLA2G5
SCHEMBL25976851 0.91 — —
SCHEMBL24304607 0.91 — —
SCHEMBL25972298 0.90 TBXAS1 (0.33) PLA2G10PLA2G1BPLA2G2APLA2G5CYP3A4
SCHEMBL24305006 0.89 P2RY10 (0.31) —
SCHEMBL25977097 0.89 — —
SCHEMBL24304428 0.88 — —
SCHEMBL25976961 0.88 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030904-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2024-07-09 — — US disclosed
US-20230250117-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2023-08-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030904-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 PLA2G10 31/4885PLA2G1B 22/4885PLA2G2A 29/4885
US-20230250117-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 PLA2G10 31/4885PLA2G1B 22/4885PLA2G2A 29/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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