SCHEMBL25976901

SCHEMBL25976901

Cc1ccccc1-c1ccc(C)c(-c2cc(-c3ccccc3C)cc[n+]2C)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.42
GRIA1 P42261 1/20 0.40
CACNG8 Q8WXS5 1/20 0.40
LCK P06239 1/20 0.40
KDR P35968 1/20 0.40
JAK3 P52333 1/20 0.40
MAPK14 Q16539 1/20 0.40
AR P10275 1/20 0.40
MCL1 Q07820 1/20 0.40
CTSD P07339 1/20 0.39
BACE1 P56817 1/20 0.39
HTR7 P34969 3/20 0.37
HTR1A P08908 1/20 0.37
PDK2 Q15119 1/20 0.37
ALOX5AP P20292 1/20 0.37
FEN1 P39748 1/20 0.37
CA12 O43570 2/20 0.37
CA9 Q16790 2/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25976525 0.94 GRIA1 (0.40) TRPA1GRIA1CACNG8LCKKDR
SCHEMBL25976900 0.94 GRIA1 (0.40) TRPA1GRIA1CACNG8LCKKDR
SCHEMBL25976902 0.93 HTR7 (0.39) TRPA1GRIA1CACNG8LCKKDR
SCHEMBL25976903 0.91 TRPA1 (0.40) TRPA1GRIA1CACNG8LCKKDR
SCHEMBL25976691 0.90 TRPA1 (0.40) TRPA1GRIA1CACNG8LCKKDR
SCHEMBL25976916 0.90 TRPA1 (0.39) TRPA1GRIA1CACNG8LCKKDR
SCHEMBL25983093 0.88 LCK (0.36) TRPA1GRIA1CACNG8LCKKDR
SCHEMBL25976951 0.87 TRPA1 (0.37) TRPA1GRIA1CACNG8LCKKDR
SCHEMBL25976690 0.87 TRPA1 (0.42) TRPA1GRIA1CACNG8LCKKDR
SCHEMBL25976524 0.87 SLC22A2 (0.42) CLK4ALDH1A1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331758-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-11725021-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11725021-B2 Organic electroluminescent materials and devices NCL, OCIAD2, OCIAD1 TRPA1 207/4885GRIA1 3263/4885CACNG8 657/4885
US-20230331758-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NCL, OCIAD2, OCIAD1 TRPA1 207/4885GRIA1 3263/4885CACNG8 657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.