Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622409 | 0.78 | GLRA1 (0.35) | ALDH1A1LMNACYP1A2CYP2D6MAPT | |
| SCHEMBL25367205 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNACYP1A2CYP2D6MAPT | |
| SCHEMBL10787258 | 0.74 | — | — | |
| SCHEMBL10787249 | 0.74 | — | — | |
| SCHEMBL25237838 | 0.74 | MAPT (0.41) | ALDH1A1LMNAMAPTPOLB | |
| SCHEMBL1463821 | 0.74 | CHRNA4 (0.57) | — | |
| SCHEMBL29257702 | 0.74 | ALDH1A1 (0.32) | ALDH1A1LMNACYP1A2CYP2D6MAPT | |
| SCHEMBL1463822 | 0.74 | CHRNA4 (0.57) | — | |
| SCHEMBL22212872 | 0.73 | — | — | |
| SCHEMBL31062632 | 0.72 | CHRNB2 (0.35) | ALDH1A1JAK3POLBJAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |