Quinoline

Quinoline

SCHEMBL259771

O=S(=O)(Cl)Cl.c1ccc2ncccc2c1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.74
NR4A2 P43354 1/20 0.48
NPC1 O15118 3/20 0.47
POLB P06746 2/20 0.47
RAB9A P51151 2/20 0.47
CYP3A4 P08684 1/20 0.45
KDM4E B2RXH2 4/20 0.44
CASP1 P29466 2/20 0.44
HTT P42858 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 2/20 0.44
TP53 P04637 2/20 0.44
TSHR P16473 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CASP7 P55210 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
HSP90AA1 P07900 1/20 0.44
HSP90AB1 P08238 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL28250633 0.98 ALDH1A1 (0.71) ALDH1A1NR4A2NPC1POLBRAB9A
Quinoline SCHEMBL28774594 0.92 ALDH1A1 (0.68) ALDH1A1NR4A2NPC1POLBRAB9A
Quinoline SCHEMBL29774014 0.89 ALDH1A1 (0.94) ALDH1A1NR4A2NPC1POLBRAB9A
Quinoline SCHEMBL28091344 0.88 ALDH1A1 (0.68) ALDH1A1NR4A2NPC1POLBRAB9A
Quinoline SCHEMBL21535 0.87 ALDH1A1 (0.74) ALDH1A1NR4A2NPC1POLBRAB9A
Quinoline SCHEMBL29710686 0.87 ALDH1A1 (0.74) ALDH1A1NR4A2NPC1POLBRAB9A
Quinoline SCHEMBL28261411 0.87 ALDH1A1 (0.74) ALDH1A1NR4A2NPC1POLBRAB9A
Quinoline SCHEMBL5186822 0.87 ALDH1A1 (0.74) ALDH1A1NR4A2NPC1POLBRAB9A
Quinoline SCHEMBL5874241 0.87 ALDH1A1 (0.74) ALDH1A1NR4A2NPC1POLBRAB9A
Quinoline SCHEMBL28142303 0.87 ALDH1A1 (0.74) ALDH1A1NR4A2NPC1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108191746-B Hydroxypyridones compound and preparation method and application thereof 暨南大学 2020-06-16 CN claimed
CN-108191746-A A kind of novel hydroxyl pyridine compounds and preparation method and application 暨南大学 2018-06-22 CN claimed
US-20110177256-A1 CURING PROCESS XEROX CORPORATION (US) 2011-07-21 US claimed
CN-100488961-C Argatroban byproduct and its synthesis, separation and identification method TIANJIN WEIJIE TECHNOLOGY CO L (CN) 2009-05-20 CN claimed
CN-101348481-A Argatroban and preparation thereof TIANJIN TAIPU PHARMACEUTICAL S (CN) 2009-01-21 CN claimed
CN-101033223-A Argatroban byproduct and its synthesis, separation and identification method TIANJIN WEIJIE TECHNOLOGY CO L (CN) 2007-09-12 CN claimed
US-6713222-B2 APPLYING ULTRAVIOLET LIGHT TO AN IMAGE COMPRISING A TONER CONTAINING AN UNSATURATED POLYESTER RESINS AND A COLORANT XEROX CORPORATION 2004-03-30 US claimed
US-20030162110-A1 Curing processes XEROX CORPORATION 2003-08-28 US claimed
US-4571377-A POLYMERIZATION EFFECTED ONLY BY APPLYING A PLURALITY OF ENERGY WAVELENGTHS BATTELLE MEMORIAL INSTITUTE (US) 1986-02-18 US claimed
CN-112368641-B Photosensitive resin composition, photosensitive sheet, cured film thereof, method for producing cured film, and electronic component 东丽株式会社 2025-05-02 CN disclosed
EP-3451348-B1 RADIATION DETECTION DEVICE AND METHOD FOR MANUFACTURING SAME TORAY INDUSTRIES (JP) 2025-02-05 EP disclosed
US-20250004372-A1 BLOCK COPOLYMER TOKYO OHKA KOGYO CO., LTD. (JP) 2025-01-02 US disclosed
CN-118900872-A Polyimide resin precursor 东京应化工业株式会社 2024-11-05 CN disclosed
EP-3351602-B1 LITHOGRAPHIC PRINTING INK, VARNISH FOR LITHOGRAPHIC INKS, AND METHOD FOR PRODUCING PRINTED MATTER USING SAID INK TORAY INDUSTRIES (JP) 2024-06-26 EP disclosed
EP-0051465-B1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-01-16 EP disclosed
US-4453970-A Herbicidal triazinyl sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-06-12 US disclosed
US-4369320-A PLANT GROWTH RETARDERS, HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-18 US disclosed
US-4192755-A Process for recovering hydrocarbons from a hydrocarbon-bearing formation TEXACO INC. (US) 1980-03-11 US disclosed
US-4192767-A Aqueous surfactant solutions and oil-in-water emulsions TEXACO INC. (US) 1980-03-11 US disclosed
US-4134415-A Pipeline transportation of heavy crude oil TEXACO INC. (US) 1979-01-16 US disclosed