Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1803766 | 0.98 | ALDH1A1 (0.39) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL2525445 | 0.98 | ALDH1A1 (0.39) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL5057071 | 0.88 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL6704637 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL2152743 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL8205166 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL12543618 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL28834557 | 0.86 | LMNA (0.45) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL4818495 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL10337324 | 0.86 | LMNA (0.45) | ALDH1A1TDP1CYP3A4TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011145933-A1 | ORGANOPHILIC POLYSILSESQUIOXANE MEMBRANES FOR SOLVENT NANOFILTRATION AND PERVAPORATION | STICHTING ENERGIEONDERZOEK CENTRUM NEDERLAND (NL) | 2011-11-24 | — | — | WO | disclosed |
| EP-0798365-A1 | Ester lubricants | ALBEMARLE CORPORATION (US) | 1997-10-01 | — | — | EP | disclosed |
| US-5271858-A | Field dependent fluids containing electrically conductive tin oxide coated materials | ENSCI INC. (US) | 1993-12-21 | — | — | US | disclosed |
| US-4062947-A | Di-N-alkylaminoglycosides, methods for their manufacture and novel intermediates useful therein, method for their use as antibacterial agents and pharmaceutical compositions useful therefor | SCHERING CORPORATION (US) | 1977-12-13 | — | — | US | disclosed |