Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597754 | 0.77 | ALDH1A1 (0.42) | CYP2D6HTTLMNAALDH1A1 | |
| SCHEMBL2599267 | 0.77 | ALDH1A1 (0.42) | CYP2D6HTTLMNAALDH1A1 | |
| SCHEMBL25772177 | 0.74 | PDK2 (0.44) | PDK2HTR7HTR2BANPEPDPP4 | |
| SCHEMBL6550873 | 0.65 | ANPEP (0.49) | PDK2ANPEPDPP4GABRA1GABRB2 | |
| SCHEMBL2597994 | 0.63 | ATM (0.41) | LMNAALDH1A1 | |
| SCHEMBL2598812 | 0.63 | ALDH1A1 (0.42) | LMNAALDH1A1 | |
| SCHEMBL19690451 | 0.61 | GABRA1 (0.39) | PDK2HTR7HTR2BGABRA1GABRB2 | |
| SCHEMBL18983054 | 0.59 | CLCN2 (0.56) | GABRA1GABRB2HTTLMNAALDH1A1 | |
| SCHEMBL13671328 | 0.59 | MEN1 (0.60) | ANPEPDPP4HTTALDH1A1 | |
| SCHEMBL23121513 | 0.58 | ANPEP (0.44) | ANPEPDPP4ELANEHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011145022-A1 | 2-PHENYL BENZOYLAMIDES | PFIZER INC. (US) | 2011-11-24 | — | — | WO | disclosed |