Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 11/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 11/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.42 |
| ▸ | CDC42 | P60953 | 1/20 | 0.42 |
| ▸ | RAC1 | P63000 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | FABP2 | P12104 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090811 | 0.83 | KMT2A (0.53) | AKR1C3AKR1C2PTGS2PTGS1CYP1A2 | |
| SCHEMBL27716564 | 0.78 | MAPT (0.62) | AKR1C3AKR1C2PTGS2PTGS1CYP1A2 | |
| SCHEMBL1002973 | 0.78 | AKR1C3 (0.50) | AKR1C3AKR1C2PTGS2PTGS1CYP1A2 | |
| SCHEMBL2598053 | 0.77 | KMT2A (0.45) | AKR1C3AKR1C2PTGS2PTGS1CYP1A2 | |
| SCHEMBL2598054 | 0.77 | KMT2A (0.45) | AKR1C3AKR1C2PTGS2PTGS1CYP1A2 | |
| SCHEMBL4129677 | 0.75 | AKR1C3 (0.47) | AKR1C3AKR1C2PTGS2PTGS1CYP1A2 | |
| SCHEMBL1708822 | 0.74 | KMT2A (0.57) | PTGS2MEN1KMT2AMAPTCYP2C9 | |
| SCHEMBL2597725 | 0.74 | ALDH1A1 (0.41) | TSHRMEN1KMT2AMAPTHPGD | |
| SCHEMBL112764 | 0.73 | AKR1C3 (0.59) | AKR1C3AKR1C2PTGS2PTGS1CYP1A2 | |
| SCHEMBL10922696 | 0.73 | PTGS1 (0.55) | AKR1C3AKR1C2PTGS2PTGS1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011145022-A1 | 2-PHENYL BENZOYLAMIDES | PFIZER INC. (US) | 2011-11-24 | — | — | WO | disclosed |