Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 12/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 12/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | DTYMK | P23919 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | CDC42 | P60953 | 1/20 | 0.38 |
| ▸ | RAC1 | P63000 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2598054 | 1.00 | KMT2A (0.45) | KMT2AMEN1HPGDNPSR1L3MBTL1 | |
| SCHEMBL2597772 | 0.87 | KMT2A (0.46) | KMT2AMEN1HPGDNPSR1L3MBTL1 | |
| SCHEMBL2597771 | 0.87 | KMT2A (0.46) | KMT2AMEN1HPGDNPSR1L3MBTL1 | |
| SCHEMBL7651884 | 0.81 | SIRT6 (0.50) | AKR1C3AKR1C2MAPTPTGS1PTGS2 | |
| SCHEMBL12185923 | 0.78 | ALDH1A1 (0.48) | KMT2AMEN1HPGDNPSR1L3MBTL1 | |
| SCHEMBL2597745 | 0.78 | AKR1C3 (0.58) | KMT2AMEN1AKR1C3AKR1C2MAPT | |
| SCHEMBL4142382 | 0.78 | GRM8 (0.50) | AKR1C3AKR1C2PTGS1PTGS2CDC42 | |
| SCHEMBL2597746 | 0.78 | AKR1C3 (0.58) | KMT2AMEN1AKR1C3AKR1C2MAPT | |
| SCHEMBL5948033 | 0.77 | AKR1C3 (0.59) | KMT2AMEN1HPGDAKR1C3AKR1C2 | |
| SCHEMBL29231640 | 0.77 | AKR1C3 (0.59) | KMT2AMEN1HPGDAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011145022-A1 | 2-PHENYL BENZOYLAMIDES | PFIZER INC. (US) | 2011-11-24 | — | — | WO | disclosed |