Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1829346 | 0.94 | TSHR (0.58) | TSHRL3MBTL1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL14777639 | 0.94 | TSHR (0.58) | TSHRL3MBTL1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9550639 | 0.89 | TSHR (0.58) | TSHRL3MBTL1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29100214 | 0.86 | TSHR (0.53) | TSHRL3MBTL1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL30641922 | 0.81 | TSHR (0.58) | TSHRSMN1; SMN2RAB9ANPC1BLM | |
| SCHEMBL1492458 | 0.81 | TSHR (0.58) | TSHRSMN1; SMN2RAB9ANPC1BLM | |
| SCHEMBL30764869 | 0.80 | TSHR (0.53) | TSHRL3MBTL1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1857263 | 0.80 | CA2 (0.59) | TSHRBLMALDH1A1LMNACYP1A2 | |
| SCHEMBL1865824 | 0.79 | CASP6 (0.55) | TSHRBLMMEN1KMT2AALDH1A1 | |
| SCHEMBL8790409 | 0.79 | TSHR (0.55) | TSHRL3MBTL1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571860-A1 | 2-PHENYL BENZOYLAMIDES | Pfizer Inc (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011145022-A1 | 2-PHENYL BENZOYLAMIDES | PFIZER INC. (US) | 2011-11-24 | — | — | WO | disclosed |