Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 8/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1155880 | 0.90 | OPRL1 (0.40) | HDAC1HDAC6P2RX7 | |
| SCHEMBL9770662 | 0.86 | MCL1 (0.49) | HDAC1HDAC6P2RX7CXCR4F2 | |
| SCHEMBL2688968 | 0.86 | HDAC1 (0.45) | HDAC1HDAC6P2RX7CXCR4F2 | |
| SCHEMBL29640806 | 0.86 | HDAC1 (0.45) | HDAC1HDAC6P2RX7CXCR4F2 | |
| SCHEMBL2305432 | 0.86 | HDAC1 (0.45) | HDAC1HDAC6P2RX7CXCR4F2 | |
| SCHEMBL27766407 | 0.83 | HDAC1 (0.44) | HDAC1HDAC6P2RX7CXCR4F2 | |
| SCHEMBL30558705 | 0.82 | HDAC1 (0.46) | HDAC1HDAC6P2RX7CXCR4ADORA2A | |
| SCHEMBL27951689 | 0.82 | HDAC1 (0.46) | HDAC1HDAC6P2RX7CXCR4ADORA2A | |
| Trifluoroacetic Acid SCHEMBL13269727 | 0.82 | ELANE (0.38) | HDAC1HDAC6P2RX7 | |
| SCHEMBL3312236 | 0.82 | HDAC1 (0.46) | HDAC1HDAC6P2RX7CXCR4ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051360-A1 | SUBSTITUTED HETEROARYL COMPOUND, AND COMPOSITION AND USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2025-02-13 | — | — | US | disclosed |
| EP-2571860-A1 | 2-PHENYL BENZOYLAMIDES | Pfizer Inc (US) | 2013-03-27 | — | — | EP | disclosed |
| US-20130072519-A1 | 2-PHENYL BENZOYLAMIDES | CONN EDWARD LEE (US) | 2013-03-21 | — | — | US | disclosed |
| WO-2011145022-A1 | 2-PHENYL BENZOYLAMIDES | PFIZER INC. (US) | 2011-11-24 | — | — | WO | disclosed |
| US-4160094-A | Tetrahydroquinoline derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1979-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072519-A1 | 2-PHENYL BENZOYLAMIDES | APOB, MTTP, HADHB | HDAC1 1474/4885HDAC6 2117/4885P2RX7 3584/4885 |
| US-20250051360-A1 | SUBSTITUTED HETEROARYL COMPOUND, AND COMPOSITION AND USE THEREOF | TYK2, JAK2, JAK1 | HDAC1 1380/4885HDAC6 711/4885P2RX7 2541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.