SCHEMBL25978459

SCHEMBL25978459

NCCOCCOCCOCCNC(=O)CCC(CCC(=O)NCCOCCOCCOCCN)(CCC(=O)NCCOCCOCCOCCN)NC(=O)CCCCCCCCCCC(=O)Oc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR2 O60603 1/20 0.35
SLC9A3 P48764 3/20 0.35
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA4 P22748 2/20 0.31
CA9 Q16790 2/20 0.31
CA14 Q9ULX7 2/20 0.31
SLC6A5 Q9Y345 2/20 0.31
LPAR1 Q92633 1/20 0.30
LPAR2 Q9HBW0 1/20 0.30
RECQL P46063 1/20 0.30
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25978452 1.00 TLR2 (0.35) TLR2SLC9A3GAAHPGDHTT
SCHEMBL25985594 0.91 SLC9A3 (0.38) SLC9A3GAALPAR1LPAR2
SCHEMBL25516224 0.87 SLC6A5 (0.43) GAASMN1; SMN2MEN1KMT2ASLC6A5
SCHEMBL25344833 0.87 L3MBTL1 (0.41) SLC9A3GAA
SCHEMBL24916689 0.86 SLC9A3 (0.36) SLC9A3GAAMEN1KMT2ALPAR1
SCHEMBL24916688 0.86 SLC9A3 (0.36) SLC9A3GAAMEN1KMT2ALPAR1
SCHEMBL25346796 0.85 SLC9A3 (0.33) SLC9A3GAALPAR1LPAR2
SCHEMBL25524359 0.85 SLC9A3 (0.33) SLC9A3GAALPAR1LPAR2
SCHEMBL25978553 0.84 SLC6A5 (0.33) GAASMN1; SMN2SLC6A5
SCHEMBL24916770 0.83 L3MBTL1 (0.40) SLC9A3GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES ASGR1, LAMP2, FCGR2A TLR2 836/4885SLC9A3 2672/4885GAA 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.