Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25750941 | 0.90 | ESRRG (0.49) | ESRRGLMNAKCNH2RAB9AMEN1 | |
| SCHEMBL25748676 | 0.89 | ESRRG (0.48) | ESRRGLMNAKCNH2RAB9AMEN1 | |
| SCHEMBL26553066 | 0.86 | ESRRG (0.49) | ESRRGLMNARAB9AMEN1KMT2A | |
| SCHEMBL27439177 | 0.83 | ESRRG (0.43) | ESRRGLMNARAB9AMEN1KMT2A | |
| SCHEMBL25567572 | 0.82 | PHLPP2 (0.49) | LMNAKCNH2L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL25978639 | 0.81 | ALDH1A1 (0.53) | KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL25978782 | 0.79 | MEN1 (0.48) | LMNARAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL25964229 | 0.77 | SMN1; SMN2 (0.53) | ESRRGLMNAKCNH2RAB9AMEN1 | |
| SCHEMBL14587224 | 0.76 | ESRRG (0.64) | ESRRGLMNAKCNH2RAB9ANPC1 | |
| SCHEMBL7367495 | 0.76 | ALDH1A1 (0.58) | LMNAKMT2AL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223318-A1 | ANTITUMOR COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Duality Biologics (Suzhou) Co., Ltd. (CN) | 2023-08-09 | — | — | EP | disclosed |