Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 11/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 3/20 | 0.35 |
| ▸ | PDE6D | O43924 | 1/20 | 0.34 |
| ▸ | PDE6A | P16499 | 1/20 | 0.34 |
| ▸ | PDE6G | P18545 | 1/20 | 0.34 |
| ▸ | PDE6B | P35913 | 1/20 | 0.34 |
| ▸ | PDE6C | P51160 | 1/20 | 0.34 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29043898 | 0.91 | USP1 (0.42) | USP1CCNE2CCNE1CDK2PDE2A | |
| SCHEMBL30462082 | 0.91 | USP1 (0.42) | USP1CCNE2CCNE1CDK2PDE2A | |
| SCHEMBL25978633 | 0.90 | USP1 (0.43) | USP1CCNE2CCNE1CDK2PDE2A | |
| SCHEMBL25978766 | 0.89 | PDE2A (0.36) | USP1PDE2A | |
| SCHEMBL29878443 | 0.88 | CSF1R (0.36) | USP1PDE2A | |
| SCHEMBL25976489 | 0.88 | PDE2A (0.36) | USP1PDE2A | |
| SCHEMBL27031506 | 0.88 | CSF1R (0.36) | USP1PDE2A | |
| SCHEMBL25978631 | 0.85 | USP1 (0.41) | USP1CCNE2CCNE1CDK2PDE2A | |
| SCHEMBL29878862 | 0.85 | PRKCQ (0.39) | USP1PDE2AMAPT | |
| SCHEMBL27031463 | 0.85 | PRKCQ (0.39) | USP1PDE2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023148643-A1 | FUSED BICYCLIC HETEROCYCLYL COMPOUNDS AS USP1 INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2023-08-10 | — | — | WO | disclosed |