Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.37 |
| ▸ | CASP7 | P55210 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30209316 | 0.91 | FEN1 (0.39) | TSHRSMN1; SMN2HSD17B10HPGDHTT | |
| SCHEMBL25789106 | 0.91 | FEN1 (0.39) | TSHRSMN1; SMN2HSD17B10HPGDHTT | |
| SCHEMBL30209253 | 0.89 | FEN1 (0.38) | TSHRSMN1; SMN2HSD17B10HPGDHTT | |
| SCHEMBL24186662 | 0.83 | ALDH1A1 (0.34) | TSHRSMN1; SMN2HSD17B10HPGDHTT | |
| SCHEMBL25978721 | 0.82 | KDM4E (0.36) | TSHRSMN1; SMN2HSD17B10HPGDHTT | |
| SCHEMBL24574867 | 0.80 | ALDH1A1 (0.34) | TSHRHSD17B10HPGDMAPK1CASP1 | |
| SCHEMBL24186664 | 0.80 | ALDH1A1 (0.34) | TSHRHSD17B10HPGDMAPK1CASP1 | |
| SCHEMBL24574873 | 0.80 | ALDH1A1 (0.34) | TSHRHSD17B10HPGDMAPK1CASP1 | |
| SCHEMBL24574883 | 0.80 | ALDH1A1 (0.34) | TSHRHSD17B10HPGDMAPK1CASP1 | |
| SCHEMBL25290986 | 0.79 | PTGER4 (0.38) | TSHRHSD17B10HPGDHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393914-A1 | IMIDAZOCYCLIC COMPOUND AND APPLICATION THEREOF | Dongbao Purple Star (Hangzhou) Biopharmaceutical Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |
| US-20230234968-A1 | METHYL-SUBSTITUTED BENZOBISOXAZOLE COMPOUND AND USE THEREOF | TONGHUA DONGBAO PHARMACEUTICAL CO., LTD. (CN) | 2023-07-27 | — | — | US | disclosed |
| US-20230234968-A1 | METHYL-SUBSTITUTED BENZOBISOXAZOLE COMPOUND AND USE THEREOF | TONGHUA DONGBAO PHARMACEUTICAL CO., LTD. (CN) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234968-A1 | METHYL-SUBSTITUTED BENZOBISOXAZOLE COMPOUND AND USE THEREOF | CYP11B2, CYP11B1, TPMT | TSHR 3651/4885SMN1; SMN2 2054/4885HSD17B10 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.