SCHEMBL25978768 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	USP1	O94782	14/20	0.39

▸	HDAC1	Q13547	1/20	0.37

▸	HDAC8	Q9BY41	1/20	0.37

▸	HDAC6	Q9UBN7	1/20	0.37

▸	HDAC5	Q9UQL6	1/20	0.37

▸	PDE2A	O00408	1/20	0.37

▸	CYP2C9	P11712	2/20	0.34

▸	KDM4E	B2RXH2	1/20	0.33

▸	MEN1	O00255	1/20	0.33

▸	HTT	P42858	1/20	0.33

▸	KMT2A	Q03164	1/20	0.33

▸	ATM	Q13315	1/20	0.33

▸	HSD17B10	Q99714	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25978766	0.90	PDE2A (0.36)	USP1PDE2A
SCHEMBL29878992	0.89	USP1 (0.39)	USP1HDAC1HDAC8HDAC6HDAC5
SCHEMBL30032845	0.89	USP1 (0.39)	USP1HDAC1HDAC8HDAC6HDAC5
SCHEMBL29296027	0.89	USP1 (0.39)	USP1HDAC1HDAC8HDAC6HDAC5
SCHEMBL27031623	0.89	USP1 (0.39)	USP1HDAC1HDAC8HDAC6HDAC5
SCHEMBL30032988	0.88	USP1 (0.39)	USP1HDAC1HDAC8HDAC6HDAC5
SCHEMBL27088234	0.88	USP1 (0.39)	USP1HDAC1HDAC8HDAC6HDAC5
SCHEMBL25978631	0.88	USP1 (0.41)	USP1PDE2A
SCHEMBL29878759	0.88	USP1 (0.39)	USP1HDAC1HDAC8HDAC6HDAC5
SCHEMBL27031709	0.88	USP1 (0.39)	USP1HDAC1HDAC8HDAC6HDAC5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023148643-A1	FUSED BICYCLIC HETEROCYCLYL COMPOUNDS AS USP1 INHIBITORS	AURIGENE ONCOLOGY LIMITED (IN)	2023-08-10	—	—	WO	disclosed