Cysteine

Cysteine

SCHEMBL2597897

NCC(=O)OC[C@H](N)C(=O)O.N[C@@H](CS)C(=O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.59
SLC7A11 Q9UPY5 1/20 0.59
SLC1A5 Q15758 1/20 0.38
NOS3 P29474 1/20 0.37
NOS1 P29475 1/20 0.37
NOS2 P35228 1/20 0.37
IDO1 P14902 2/20 0.36
ENPEP Q07075 4/20 0.35
GSR P00390 2/20 0.34
P2RY10 O00398 3/20 0.33
GPR174 Q9BXC1 3/20 0.33
GPR34 Q9UPC5 2/20 0.33
SLC1A1 P43005 2/20 0.32
CPB2 Q96IY4 1/20 0.32
SLC7A5 Q01650 1/20 0.32
GRM8 O00222 1/20 0.32
GRM6 O15303 1/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL352049 0.90 SLC1A5 (0.43) PTGS1SLC7A11SLC1A5NOS3NOS1
SCHEMBL3502798 0.90 SLC1A5 (0.43) PTGS1SLC7A11SLC1A5NOS3NOS1
Glycine SCHEMBL8588130 0.86 GLRA1 (0.42) PTGS1SLC7A11SLC1A5NOS3NOS1
SCHEMBL3075848 0.86 PTGS1 (0.43) PTGS1SLC7A11SLC1A5NOS3NOS1
SCHEMBL4752999 0.85 SLC1A5 (0.40) PTGS1SLC7A11SLC1A5NOS3NOS1
SCHEMBL12500454 0.85 SLC1A5 (0.40) PTGS1SLC7A11SLC1A5NOS3NOS1
SCHEMBL16058499 0.84 PTGS1 (0.48) PTGS1SLC7A11SLC1A5NOS3NOS1
Cysteine SCHEMBL15417922 0.84 PTGS1 (0.42) PTGS1SLC7A11SLC1A5NOS3NOS1
Alanine SCHEMBL5168125 0.83 SLC7A5 (0.42) PTGS1SLC7A11SLC1A5NOS3NOS1
Serine SCHEMBL7925097 0.83 SLC1A5 (0.42) PTGS1SLC7A11SLC1A5NOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2571897-B1 NOVEL GLUCAGON LIKE PEPTIDE ANALOGS, COMPOSITION, AND METHOD OF USE BETTA PHARMACEUTICALS CO LTD (CN) 2014-11-05 EP claimed
US-20130203672-A1 Novel Glucagon Like Peptide Analogs, Composition, and Method of Use BETTA PHARMACEUTICALS CO., LTD (CN) 2013-08-08 US claimed
EP-2571897-A1 NOVEL GLUCAGON LIKE PEPTIDE ANALOGS, COMPOSITION, AND METHOD OF USE Zhejiang Beta Pharma Inc. (CN) 2013-03-27 EP claimed
WO-2011143788-A1 NOVEL GLUCAGON LIKE PEPTIDE ANALOGS, COMPOSITION, AND METHOD OF USE ZHEJIANG BETA PHARMA INC. (CN) 2011-11-24 WO claimed
US-20210116462-A1 Methods and Compositions for the Diagnosis and Treatment of Kawasaki Disease MOMENTA PHARMACEUTICALS, INC. 2021-04-22 US disclosed
CN-110317766-B Genetically engineered bacterium capable of highly producing L-cysteine, construction method and application 浙江工业大学 2020-08-28 CN disclosed
EP-3137907-A2 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF KAWASAKI DISEASE Momenta Pharmaceuticals, Inc. (US) 2017-03-08 EP disclosed
US-20170052200-A1 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF KAWASAKI DISEASE MOMENTA PHARMACEUTICALS, INC. 2017-02-23 US disclosed
US-9487570-B2 Glucagon like peptide analogs, composition, and method of use BETTA PHARMACEUTICALS CO., LTD (CN) 2016-11-08 US disclosed
WO-2016161333-A2 COMPOSITIONS COMPRISING BIOCONJUGATES PURDUE RESEARCH FOUNDATION (US) 2016-10-06 WO disclosed
WO-2015168602-A2 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF KAWASAKI DISEASE MOMENTA PHARMACEUTICALS, INC. (US) 2015-11-05 WO disclosed
EP-2571897-B1 NOVEL GLUCAGON LIKE PEPTIDE ANALOGS, COMPOSITION, AND METHOD OF USE BETTA PHARMACEUTICALS CO LTD (CN) 2014-11-05 EP disclosed
US-20130203672-A1 Novel Glucagon Like Peptide Analogs, Composition, and Method of Use BETTA PHARMACEUTICALS CO., LTD (CN) 2013-08-08 US disclosed
EP-2571897-A1 NOVEL GLUCAGON LIKE PEPTIDE ANALOGS, COMPOSITION, AND METHOD OF USE Zhejiang Beta Pharma Inc. (CN) 2013-03-27 EP disclosed
WO-2011143788-A1 NOVEL GLUCAGON LIKE PEPTIDE ANALOGS, COMPOSITION, AND METHOD OF USE ZHEJIANG BETA PHARMA INC. (CN) 2011-11-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130203672-A1 Novel Glucagon Like Peptide Analogs, Composition, and Method of Use IAPP, GLP1R, GIPR PTGS1 3042/4885SLC7A11 1980/4885SLC1A5 1328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.