SCHEMBL352049

SCHEMBL352049

NCC(=O)OC[C@H](N)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A5 Q15758 1/20 0.43
NOS3 P29474 1/20 0.42
NOS1 P29475 1/20 0.42
NOS2 P35228 1/20 0.42
IDO1 P14902 2/20 0.41
PTGS1 P23219 1/20 0.41
SLC7A11 Q9UPY5 1/20 0.41
GSR P00390 2/20 0.40
SLC1A1 P43005 3/20 0.38
GRIK1 P39086 2/20 0.38
GRIK2 Q13002 2/20 0.38
GRM1 Q13255 2/20 0.38
GRM2 Q14416 2/20 0.38
SLC7A5 Q01650 1/20 0.38
GRM8 O00222 1/20 0.38
GRM6 O15303 1/20 0.38
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
CYP1A2 P05177 1/20 0.38
GRM5 P41594 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3502798 1.00 SLC1A5 (0.43) SLC1A5NOS3NOS1NOS2IDO1
Glycine SCHEMBL8588130 0.96 GLRA1 (0.42) SLC1A5NOS3NOS1NOS2IDO1
SCHEMBL4752999 0.94 SLC1A5 (0.40) SLC1A5NOS3NOS1NOS2IDO1
SCHEMBL12500454 0.94 SLC1A5 (0.40) SLC1A5NOS3NOS1NOS2IDO1
Serine SCHEMBL7925097 0.92 SLC1A5 (0.42) SLC1A5NOS3NOS1NOS2IDO1
Alanine SCHEMBL5168125 0.92 SLC7A5 (0.42) SLC1A5NOS3NOS1NOS2IDO1
Aspartic Acid SCHEMBL15399013 0.90 GRIK1 (0.38) SLC1A5NOS3NOS1NOS2IDO1
Cysteine SCHEMBL2597897 0.90 PTGS1 (0.59) SLC1A5NOS3NOS1NOS2IDO1
Glycine SCHEMBL1548291 0.90 SLC1A5 (0.38) SLC1A5NOS3NOS1NOS2IDO1
SCHEMBL18152975 0.89 SLC1A5 (0.37) SLC1A5NOS3NOS1NOS2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11649326-B2 Functional, segregated, charged telodendrimers and nanocarriers and methods of making and using same THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-05-16 US claimed
CN-115128277-A Group of biomarkers for evaluating PCOS (Primary biliary cirrhosis) oocyte quality, application and screening method 深圳中山泌尿外科医院 2022-09-30 CN claimed
EP-3347053-B1 FUNCTIONAL, SEGREGATED, CHARGED TELODENDRIMERS AND NANOCARRIERS AND METHODS OF MAKING AND USING SAME THE RESEARCH FOUNDATION FOR STATE UNIV OF NEW YORK (US) 2022-05-25 EP claimed
US-11219692-B2 Porphyrin modified telodendrimers THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-01-11 US claimed
US-10967003-B2 Functional segregated telodendrimers and nanocarriers and methods of making and using same THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2021-04-06 US claimed
US-20200254012-A1 FUNCTIONAL SEGREGATED TELODENDRIMERS AND NANOCARRIERS AND METHODS OF MAKING AND USING SAME THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK 2020-08-13 US claimed
EP-3035968-B1 TELODENDRIMERS AND NANOCARRIERS AND METHODS OF USING SAME UNIV NEW YORK STATE RES FOUND (US) 2020-05-06 EP claimed
US-20200046841-A1 PORPHYRIN MODIFIED TELODENDRIMERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-02-13 US claimed
US-10463694-B2 Functional segregated telodendrimers and nanocarriers and methods of making and using same THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2019-11-05 US claimed
EP-3512569-A1 IMPROVED HYBRID TELODENDRIMERS The Regents of The University of California (US) 2019-07-24 EP claimed
EP-2707419-A2 REVERSIBLY CROSSLINKED MICELLE SYSTEMS The Regents of the University of California (US) 2014-03-19 EP claimed
WO-2012158622-A2 REVERSIBLY CROSSLINKED MICELLE SYSTEMS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-11-22 WO claimed
US-20090191610-A1 Microorganisms With Increased Efficiency for Methionine Synthesis EVONIK DEGUSSA GMBH (DE) 2009-07-30 US claimed
EP-1931784-A2 MICROORGANISMS WITH INCREASED EFFICIENCY FOR METHIONINE SYNTHESIS BASF SE (DE) 2008-06-18 EP claimed
WO-2007020295-A2 MICROORGANISMS WITH INCREASED EFFICIENCY FOR METHIONINE SYNTHESIS BASF AG (DE) 2007-02-22 WO claimed
WO-2002086153-A1 DETERMINING RESISTANCE TO A $G(b)-LACTAM-CONTAINING ANTIBIOTIC BY COMPARING THE RATIO OF TWO $G(b)-LACTAMASE GENES DIATECH PTY LTD (AU) 2002-10-31 WO claimed
WO-2002053526-A1 NEW COMPOUNDS FOR USE AS INTERMEDIATES IN LINEAR BLOCK POLYMER AND NEW LINEAR BLOCK POLYMER ARTIMPLANT AB (SE) 2002-07-11 WO claimed
WO-2002053616-A1 NEW LINEAR BLOCK POLYMER ARTIMPLANT AB (SE) 2002-07-11 WO claimed
EP-0332225-B1 ANTIBODY TO POLYPEPTIDES COMPLEMENTARY TO PEPTIDES OR PROTEINS HAVING AN AMINO ACID SEQUENCE OR NUCLEOTIDE CODING SEQUENCE AT LEAST PARTIALLY KNOWN AND METHODS OF DESIGN THEREFOR BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1993-04-21 EP claimed
US-4360458-A PEPTIDE ANTIBIOTICS, ANTIBIOTIC BBM-928 BRISTOL-MYERS COMPANY (US) 1982-11-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200254012-A1 FUNCTIONAL SEGREGATED TELODENDRIMERS AND NANOCARRIERS AND METHODS OF MAKING AND USING SAME TTI2, TELO2, BICRA SLC1A5 3340/4885NOS3 2719/4885NOS1 3439/4885
US-20200046841-A1 PORPHYRIN MODIFIED TELODENDRIMERS CETP, NR1H4, ABCB4 SLC1A5 884/4885NOS3 4301/4885NOS1 4123/4885
US-10967003-B2 Functional segregated telodendrimers and nanocarriers and methods of making and using same TTI2, TELO2, BICRA SLC1A5 3340/4885NOS3 2719/4885NOS1 3439/4885
US-10463694-B2 Functional segregated telodendrimers and nanocarriers and methods of making and using same TTI2, TELO2, BICRA SLC1A5 3340/4885NOS3 2719/4885NOS1 3439/4885
US-11649326-B2 Functional, segregated, charged telodendrimers and nanocarriers and methods of making and using same TSPO, TBCA, TTI2 SLC1A5 299/4885NOS3 4192/4885NOS1 4083/4885
US-11219692-B2 Porphyrin modified telodendrimers CETP, NR1H4, ABCB4 SLC1A5 884/4885NOS3 4301/4885NOS1 4123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.