Serine

Serine

SCHEMBL7925097

NCC(=O)OC[C@H](N)C(=O)O.N[C@@H](CO)C(=O)O

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A5 Q15758 1/20 0.42
SLC1A1 P43005 3/20 0.39
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
NOS2 P35228 1/20 0.38
IDO1 P14902 2/20 0.37
PTGS1 P23219 1/20 0.35
SLC7A11 Q9UPY5 1/20 0.35
GSR P00390 2/20 0.35
P2RY10 O00398 3/20 0.34
GPR174 Q9BXC1 3/20 0.34
GPR34 Q9UPC5 2/20 0.34
GRIK1 P39086 2/20 0.33
GRIK2 Q13002 2/20 0.33
GRM1 Q13255 2/20 0.33
GRM2 Q14416 2/20 0.33
SLC7A5 Q01650 1/20 0.33
GRM8 O00222 1/20 0.33
GRM6 O15303 1/20 0.33
GRIN2D O15399 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serine SCHEMBL9702742 0.96 SLC1A5 (0.41) SLC1A5SLC1A1NOS3NOS1NOS2
Serine SCHEMBL3517747 0.96 SLC1A5 (0.41) SLC1A5SLC1A1NOS3NOS1NOS2
Serine SCHEMBL18191257 0.96 SLC1A5 (0.41) SLC1A5SLC1A1NOS3NOS1NOS2
Serine SCHEMBL17072285 0.93 SLC1A5 (0.39) SLC1A5SLC1A1NOS3NOS1NOS2
SCHEMBL352049 0.92 SLC1A5 (0.43) SLC1A5SLC1A1NOS3NOS1NOS2
SCHEMBL3502798 0.92 SLC1A5 (0.43) SLC1A5SLC1A1NOS3NOS1NOS2
Serine SCHEMBL15094110 0.92 SLC1A5 (0.38) SLC1A5SLC1A1NOS3NOS1NOS2
Serine SCHEMBL3821533 0.92 SLC1A5 (0.38) SLC1A5SLC1A1NOS3NOS1NOS2
Serine SCHEMBL3961258 0.90 SLC1A5 (0.36) SLC1A5SLC1A1NOS3NOS1NOS2
SCHEMBL16678086 0.90 SLC1A5 (0.36) SLC1A5SLC1A1NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6235283-B1 AN ISOLATED POLYPEPTIDE ENCODED BY A POLYNUCLEOTIDE SEQUENCE THAT HYBRIDIZES TO THE COMPLEMENTARY STRAND OF AN ISOLATED POLYNUCLEOTIDE SEQUENCE ENCODING SPECIFIC AMINO ACID SEQUENCE; PRODUCES IMMUNE RESPONSE AGAINST TICK INFESTATIONINFESTATION BIOTECHNOLOGY AUSTRALIA PTY. LTD. (AU) 2001-05-22 US disclosed
US-5587311-A PURIFIED ANTIGENS AND RECOMBINANT EXPRESSION PRODUCTS WHICH PROVIDE VACCINES TO PROTECT CATTLE AGAINST TICK INFESTATION BIOTECHNOLOGY AUSTRALIA PTY. LTD. (AU) 1996-12-24 US disclosed