Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22686036 | 0.90 | HDAC1 (0.51) | HDAC1HDAC6HDAC8MTORKMT2A | |
| SCHEMBL16211817 | 0.89 | ALDH1A1 (0.50) | HDAC1HDAC6HDAC8MTORNPC1 | |
| SCHEMBL16211578 | 0.88 | HDAC1 (0.49) | HDAC1HDAC6HDAC8MTORNPC1 | |
| SCHEMBL25980466 | 0.86 | HDAC1 (0.46) | HDAC1HDAC6HDAC8MTORNPC1 | |
| SCHEMBL25980532 | 0.80 | HDAC1 (0.46) | HDAC1HDAC6HDAC8NPC1RAB9A | |
| SCHEMBL17623522 | 0.79 | HDAC1 (0.49) | HDAC1HDAC6HDAC8NPC1RAB9A | |
| SCHEMBL25980727 | 0.78 | HDAC6 (0.48) | HDAC1HDAC6HDAC8HDAC5PDK2 | |
| SCHEMBL16221442 | 0.78 | HDAC6 (0.48) | HDAC1HDAC6HDAC8 | |
| SCHEMBL16211622 | 0.77 | HDAC1 (0.51) | HDAC1HDAC6HDAC8KMT2AHDAC5 | |
| SCHEMBL22686049 | 0.77 | LTB4R2 (0.53) | HDAC1HDAC6HDAC8MTORNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248735-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248735-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | NR1H2, CFTR, CYP11B2 | HDAC1 1635/4885HDAC6 997/4885HDAC8 2983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.