Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16211625 | 0.92 | CYP2D6 (0.54) | CYP2D6HTR1ACYP3A4ADRA1AMEN1 | |
| SCHEMBL16211821 | 0.90 | CYP2D6 (0.56) | CYP2D6HTR1ACYP3A4ADRA1AMEN1 | |
| SCHEMBL25979330 | 0.85 | TSHR (0.44) | MEN1ALDH1A1KMT2ATSHR | |
| SCHEMBL25979304 | 0.85 | CYP3A4 (0.43) | CYP2D6HTR1ACYP3A4ADRA1AMEN1 | |
| SCHEMBL25979342 | 0.85 | POLB (0.44) | CYP2D6CYP3A4MEN1ALDH1A1KMT2A | |
| SCHEMBL25979317 | 0.84 | TSHR (0.46) | CYP2D6CYP3A4MEN1ALDH1A1KMT2A | |
| SCHEMBL25980746 | 0.84 | TSHR (0.46) | CYP2D6CYP3A4MEN1ALDH1A1KMT2A | |
| SCHEMBL25979283 | 0.83 | SMN1; SMN2 (0.46) | CYP2D6CYP3A4MEN1ALDH1A1KMT2A | |
| SCHEMBL25980729 | 0.82 | TSHR (0.41) | CYP2D6CYP3A4MEN1ALDH1A1KMT2A | |
| SCHEMBL25980756 | 0.82 | OPRM1 (0.41) | CYP2D6HTR1ACYP3A4MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248735-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248735-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | NR1H2, CFTR, CYP11B2 | CYP2D6 1618/4885HTR1A 3822/4885CYP3A4 1676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.