Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | DUT | P33316 | 2/20 | 0.35 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.35 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1938808 | 1.00 | CRBN (0.42) | CRBNPOLBHSD17B10PTGS2DDB1 | |
| SCHEMBL16289906 | 0.84 | CRBN (0.40) | CRBNPOLBHSD17B10PTGS2DDB1 | |
| SCHEMBL5290093 | 0.78 | CRBN (0.46) | CRBNPOLBHSD17B10PTGS2DDB1 | |
| SCHEMBL4551699 | 0.73 | PKM (0.41) | CRBNDDB1ALDH1A1PKMDUT | |
| SCHEMBL725455 | 0.73 | CRBN (0.43) | CRBNPOLBHSD17B10PTGS2DDB1 | |
| SCHEMBL2787886 | 0.73 | CRBN (0.43) | CRBNPOLBHSD17B10PTGS2DDB1 | |
| SCHEMBL6666895 | 0.72 | POLB (0.47) | CRBNPOLBHSD17B10PTGS2DDB1 | |
| SCHEMBL1344880 | 0.72 | CRBN (0.50) | CRBNPOLBHSD17B10DDB1PKM | |
| SCHEMBL2990979 | 0.72 | CRBN (0.50) | CRBNPOLBHSD17B10DDB1PKM | |
| SCHEMBL14237174 | 0.70 | POLB (0.45) | CRBNPOLBHSD17B10DDB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2572192-A2 | A GENERAL MASS SPECTROMETRY ASSAY USING CONTINUOUSLY ELUTING CO-FRACTIONATING REPORTERS OF MASS SPECTROMETRY DETECTION EFFICIENCY | The UAB Research Foundation (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011146521-A2 | A GENERAL MASS SPECTROMETRY ASSAY USING CONTINUOUSLY ELUTING CO-FRACTIONATING REPORTERS OF MASS SPECTROMETRY DETECTION EFFICIENCY | THE UAB RESEARCH FOUNDATION (US) | 2011-11-24 | — | — | WO | disclosed |