Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16211277 | 0.90 | HDAC1 (0.61) | HDAC4KCNH2HDAC1TSHROPRM1 | |
| SCHEMBL25979342 | 0.90 | POLB (0.44) | TSHROPRM1POLBALDH1A1HPGD | |
| SCHEMBL25980746 | 0.88 | TSHR (0.46) | TSHRPOLBALDH1A1HPGDKDM4E | |
| SCHEMBL25979317 | 0.88 | TSHR (0.46) | TSHRPOLBALDH1A1HPGDKDM4E | |
| SCHEMBL16211849 | 0.88 | ALDH1A1 (0.56) | TSHROPRM1SIGMAR1POLBALDH1A1 | |
| SCHEMBL25979330 | 0.87 | TSHR (0.44) | TSHROPRM1POLBALDH1A1HPGD | |
| SCHEMBL25979283 | 0.87 | SMN1; SMN2 (0.46) | TSHRPOLBALDH1A1HPGDKDM4E | |
| SCHEMBL25980729 | 0.84 | TSHR (0.41) | TSHROPRM1POLBALDH1A1HPGD | |
| SCHEMBL25979300 | 0.84 | HTT (0.49) | TSHRPOLBALDH1A1HPGDKDM4E | |
| SCHEMBL25979075 | 0.83 | HDAC4 (0.50) | HDAC4KCNH2HDAC1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248735-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248735-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | NR1H2, CFTR, CYP11B2 | HDAC4 3002/4885KCNH2 3526/4885HDAC1 1635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.