Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | MLYCD | O95822 | 7/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25979588 | 0.90 | HDAC6 (0.50) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL16211813 | 0.88 | HDAC6 (0.43) | HDAC6HDAC1HDAC8MLYCDHDAC3 | |
| SCHEMBL25979600 | 0.87 | HDAC6 (0.41) | HDAC6HDAC1HDAC8HDAC3ALDH1A1 | |
| SCHEMBL25980709 | 0.86 | MLYCD (0.48) | HDAC6HDAC1HDAC8MLYCDHDAC3 | |
| SCHEMBL29878916 | 0.85 | MAPK1 (0.43) | HDAC6HDAC1HDAC8MLYCDHDAC3 | |
| SCHEMBL17623522 | 0.84 | HDAC1 (0.49) | HDAC6HDAC1HDAC8MLYCDALDH1A1 | |
| SCHEMBL16211386 | 0.84 | HDAC6 (0.51) | HDAC6HDAC1HDAC8ALDH1A1TP53 | |
| SCHEMBL23436417 | 0.83 | NPC1 (0.48) | HDAC6HDAC1HDAC8MLYCDALDH1A1 | |
| SCHEMBL16211346 | 0.83 | STAT3 (0.46) | HDAC6HDAC1HDAC8MLYCDHDAC3 | |
| SCHEMBL18910372 | 0.83 | MLYCD (0.46) | HDAC6HDAC1HDAC8MLYCDHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248735-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248735-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | NR1H2, CFTR, CYP11B2 | HDAC6 997/4885HDAC1 1635/4885HDAC8 2983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.