SCHEMBL25979709

SCHEMBL25979709

O=C(CCC(CCC(=O)NCCOCCOCCn1cc(CCCO[C@H]2C[C@@H](O)[C@@H](O)[C@@H](CO)O2)nn1)(CCC(=O)NCCOCCOCCn1cc(CCCO[C@H]2C[C@@H](O)[C@@H](O)[C@@H](CO)O2)nn1)NC(=O)CCCCCCCCCCC(=O)Oc1c(F)c(F)c(F)c(F)c1F)NCCOCCOCCn1cc(CCCO[C@H]2C[C@@H](O)[C@@H](O)[C@@H](CO)O2)nn1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 4/20 0.39
GLA P06280 2/20 0.37
GBA1 P04062 2/20 0.35
PKM P14618 1/20 0.34
CLEC4M Q9H2X3 3/20 0.34
OPRM1 P35372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25506227 0.93 LGALS3 (0.51) LGALS3GLAPKMCLEC4M
SCHEMBL25979960 0.91 LGALS3 (0.37) LGALS3GLAGBA1PKMCLEC4M
SCHEMBL25506055 0.88 LGALS3 (0.41) LGALS3GLAGBA1CLEC4M
SCHEMBL25505788 0.87 LGALS3 (0.40) LGALS3GLAGBA1CLEC4MOPRM1
SCHEMBL25505637 0.87 LGALS3 (0.44) LGALS3PKMCLEC4MOPRM1
SCHEMBL25523201 0.87 LGALS3 (0.44) LGALS3PKMCLEC4MOPRM1
SCHEMBL25908468 0.87 LGALS3 (0.56) LGALS3GLACLEC4M
SCHEMBL25979532 0.84 LGALS3 (0.40) LGALS3GLAGBA1CLEC4M
SCHEMBL25344774 0.82 LGALS3 (0.49) LGALS3GLAPKMCLEC4MOPRM1
SCHEMBL25346846 0.82 LGALS3 (0.47) LGALS3GLAGBA1CLEC4M

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES ASGR1, LAMP2, FCGR2A LGALS3 264/4885GLA 384/4885GBA1 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.