SCHEMBL25523201

SCHEMBL25523201

O=C(CCOCCOCCC(=O)Oc1c(F)c(F)c(F)c(F)c1F)NCCOCCOCCOCCn1cc(CCO[C@H]2C[C@@H](O)[C@@H](O)[C@@H](CO)O2)nn1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 4/20 0.44
OPRM1 P35372 1/20 0.34
PKM P14618 1/20 0.33
XIAP P98170 1/20 0.33
BIRC2 Q13490 1/20 0.33
CLEC4M Q9H2X3 2/20 0.33
F2RL1 P55085 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25505637 1.00 LGALS3 (0.44) LGALS3OPRM1PKMXIAPBIRC2
SCHEMBL25979427 0.95 LGALS3 (0.44) LGALS3CLEC4M
SCHEMBL25523254 0.94 LGALS3 (0.42) LGALS3CLEC4M
SCHEMBL25523320 0.93 LGALS3 (0.41) LGALS3CLEC4M
SCHEMBL25983012 0.92 LGALS3 (0.40) LGALS3CLEC4M
SCHEMBL25979532 0.90 LGALS3 (0.40) LGALS3CLEC4M
SCHEMBL25979459 0.90 LGALS3 (0.39) LGALS3CLEC4M
SCHEMBL29332026 0.89 LGALS3 (0.37) LGALS3OPRM1XIAPBIRC2F2RL1
SCHEMBL25495188 0.87 LGALS3 (0.50) LGALS3OPRM1PKMXIAPBIRC2
SCHEMBL25979709 0.87 LGALS3 (0.39) LGALS3OPRM1PKMCLEC4M

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. 2023-08-10 US disclosed
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates M6PR, ASGR1, IGF2R LGALS3 293/4885OPRM1 1331/4885PKM 2229/4885
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES ASGR1, LAMP2, FCGR2A LGALS3 264/4885OPRM1 3060/4885PKM 3998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.