Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16211267 | 0.90 | HDAC6 (0.48) | HDAC6HDAC11HDAC8HDAC3HDAC1 | |
| SCHEMBL16211665 | 0.90 | HDAC6 (0.48) | HDAC6HDAC11HDAC8HDAC3HDAC1 | |
| SCHEMBL16211265 | 0.90 | HDAC6 (0.48) | HDAC6HDAC11HDAC8HDAC3HDAC1 | |
| SCHEMBL25981501 | 0.88 | HDAC6 (0.49) | HDAC6HDAC11HDAC8HDAC3HDAC1 | |
| SCHEMBL25981478 | 0.88 | HDAC6 (0.47) | HDAC6HDAC11HDAC8HDAC3HDAC1 | |
| SCHEMBL16211719 | 0.82 | HDAC6 (0.52) | HDAC6HDAC11HDAC8HDAC1 | |
| SCHEMBL16211390 | 0.81 | HDAC6 (0.52) | HDAC6HDAC11HDAC8HDAC3HDAC1 | |
| SCHEMBL25981390 | 0.81 | HDAC6 (0.41) | HDAC6HDAC8HDAC3HDAC1HDAC4 | |
| SCHEMBL16211373 | 0.80 | SLC6A5 (0.41) | LSSSLC6A5TEAD1 | |
| SCHEMBL16211371 | 0.80 | SLC6A5 (0.41) | LSSSLC6A5TEAD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248735-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248735-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | NR1H2, CFTR, CYP11B2 | HDAC6 997/4885HDAC11 1490/4885HDAC8 2983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.