Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 3/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25981781 | 0.87 | HDAC1 (0.49) | HDAC1HDAC6HDAC8HDAC5HIF1A | |
| SCHEMBL16211279 | 0.86 | HDAC6 (0.49) | HDAC1HDAC6HDAC8HDAC5AOC3 | |
| SCHEMBL25979197 | 0.85 | HDAC1 (0.44) | HDAC1HDAC6HDAC8GRIN2BFPR2 | |
| SCHEMBL25980840 | 0.85 | HDAC6 (0.47) | HDAC1HDAC6HDAC8HDAC5HIF1A | |
| SCHEMBL25980858 | 0.85 | HDAC6 (0.47) | HDAC1HDAC6HDAC8HDAC5HIF1A | |
| SCHEMBL25980822 | 0.84 | HDAC1 (0.46) | HDAC1HDAC6HDAC8HDAC5AOC3 | |
| SCHEMBL25980903 | 0.84 | HDAC1 (0.43) | HDAC1HDAC6HDAC8AOC3ALDH1A1 | |
| SCHEMBL25980892 | 0.84 | HDAC1 (0.46) | HDAC1HDAC6HDAC8HDAC5AOC3 | |
| SCHEMBL16211519 | 0.84 | HDAC1 (0.49) | HDAC1HDAC6HDAC8HDAC5AOC3 | |
| SCHEMBL25981788 | 0.84 | HDAC1 (0.47) | HDAC1HDAC6HDAC8HDAC5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248735-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248735-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | NR1H2, CFTR, CYP11B2 | HDAC1 1635/4885HDAC6 997/4885HDAC8 2983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.