Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MLYCD | O95822 | 12/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16211522 | 0.90 | HDAC1 (0.45) | HDAC1HDAC8HDAC6MLYCDCD274 | |
| SCHEMBL25979180 | 0.89 | MAPT (0.46) | HDAC1HDAC8HDAC6MLYCDCD274 | |
| SCHEMBL25979238 | 0.89 | HDAC1 (0.51) | HDAC1HDAC8HDAC6MLYCDCD274 | |
| SCHEMBL25979143 | 0.88 | HDAC1 (0.46) | HDAC1HDAC8HDAC6MLYCDCD274 | |
| SCHEMBL16211497 | 0.88 | ALDH1A1 (0.46) | HDAC1HDAC8HDAC6MLYCDERN1 | |
| SCHEMBL25979215 | 0.87 | MLYCD (0.41) | HDAC1HDAC8HDAC6MLYCDCD274 | |
| SCHEMBL25980828 | 0.85 | HDAC1 (0.46) | HDAC1HDAC8HDAC6MLYCDGRIN2B | |
| SCHEMBL25981781 | 0.85 | HDAC1 (0.49) | HDAC1HDAC8HDAC6MLYCDNPC1 | |
| SCHEMBL25980601 | 0.84 | MLYCD (0.43) | HDAC1HDAC8HDAC6MLYCDCD274 | |
| SCHEMBL25979184 | 0.84 | ALDH1A1 (0.41) | HDAC1HDAC8HDAC6MLYCDCD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248735-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248735-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | NR1H2, CFTR, CYP11B2 | HDAC1 1635/4885HDAC8 2983/4885HDAC6 997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.