Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8386069 | 0.73 | ESR1 (0.44) | ESR1ESR2ALDH1A1RAB9ANPC1 | |
| SCHEMBL8384580 | 0.73 | ESR1 (0.44) | ESR1ESR2ALDH1A1RAB9ANPC1 | |
| SCHEMBL242095 | 0.69 | ALDH1A1 (0.40) | ESR1ESR2ALDH1A1RAB9ANPC1 | |
| SCHEMBL464991 | 0.69 | ALDH1A1 (0.40) | ESR1ESR2ALDH1A1RAB9ANPC1 | |
| SCHEMBL8385033 | 0.67 | ESR1 (0.34) | ESR1ESR2ALDH1A1MAPK1TSHR | |
| SCHEMBL15975758 | 0.67 | ESR1 (0.43) | ESR1ESR2ALDH1A1RAB9ANPC1 | |
| SCHEMBL126319 | 0.67 | ESR1 (0.43) | ESR1ESR2ALDH1A1RAB9ANPC1 | |
| SCHEMBL12879524 | 0.67 | ESR1 (0.43) | ESR1ESR2ALDH1A1RAB9ANPC1 | |
| SCHEMBL103830 | 0.67 | ESR1 (0.43) | ESR1ESR2ALDH1A1RAB9ANPC1 | |
| SCHEMBL15975757 | 0.67 | ESR1 (0.43) | ESR1ESR2ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987493-B2 | Process for synthesis of silane dipeptide analogs | Temple University—Of the Commonwealth System of Higher Education (US) | 2015-03-24 | — | — | US | disclosed |
| US-20130096335-A1 | PROCESS FOR SYNTHESIS OF SILANE DIPEPTIDE ANALOGS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2013-04-18 | — | — | US | disclosed |
| WO-2011146842-A1 | PROCESS FOR SYNTHESIS OF SILANE DIPEPTIDE ANALOGS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2011-11-24 | — | — | WO | disclosed |
| EP-0630933-B1 | A method of producing a semiconducting material | NIPPON OIL CO LTD (JP) | 1999-04-14 | — | — | EP | disclosed |
| US-5700400-A | Method for producing a semiconducting material | NIPPON OIL CO., LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| EP-0551771-B1 | Process for producing polysilanes | NIPPON OIL CO LTD (JP) | 1997-07-30 | — | — | EP | disclosed |
| US-5620531-A | Photovoltaic element | NIPPON OIL CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0717451-A2 | Photovoltaic element | NIPPON OIL CO., LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |
| EP-0630933-A2 | A method of producing a semiconducting material | NIPPON OIL CO. LTD. (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-5304622-A | Process for producing polysilanes | NIPPON OIL COMPANY, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0551771-A2 | Process for producing polysilanes | NIPPON OIL CO. LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096335-A1 | PROCESS FOR SYNTHESIS OF SILANE DIPEPTIDE ANALOGS | VIP, DNPEP, SSTR4 | ESR1 2920/4885ESR2 2708/4885ALDH1A1 4009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.