SCHEMBL8384580

SCHEMBL8384580

C[Si](C)([Na])c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
HPGD P15428 2/20 0.36
KDM4E B2RXH2 1/20 0.36
NR1H2 P55055 2/20 0.35
NR1H3 Q13133 2/20 0.35
TSHR P16473 3/20 0.35
LMNA P02545 1/20 0.35
ALOX12 P18054 1/20 0.35
ACHE P22303 1/20 0.35
MAPT P10636 1/20 0.34
CCR1 P32246 1/20 0.33
CCR8 P51685 1/20 0.33
ALDH1A1 P00352 3/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8386069 0.81 ESR1 (0.44) ESR1ESR2HPGDKDM4ENR1H2
SCHEMBL713818 0.75 ESR1 (0.44) ESR1ESR2HPGDKDM4ENR1H2
SCHEMBL2598141 0.73 ESR1 (0.36) ESR1ESR2HPGDKDM4ETSHR
SCHEMBL239179 0.73 ESR1 (0.48) ESR1ESR2HPGDNR1H2NR1H3
SCHEMBL92396 0.73 ESR1 (0.48) ESR1ESR2HPGDNR1H2NR1H3
SCHEMBL2169977 0.73 ESR1 (0.48) ESR1ESR2HPGDNR1H2NR1H3
SCHEMBL63526 0.73 ESR1 (0.70) ESR1ESR2HPGDNR1H2NR1H3
SCHEMBL439492 0.73 ESR1 (0.48) ESR1ESR2HPGDNR1H2NR1H3
Methane SCHEMBL28815257 0.71 ESR1 (0.46) ESR1ESR2HPGDNR1H2NR1H3
SCHEMBL7768857 0.71 ESR1 (0.46) ESR1ESR2HPGDNR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0630933-B1 A method of producing a semiconducting material NIPPON OIL CO LTD (JP) 1999-04-14 EP disclosed
US-5700400-A Method for producing a semiconducting material NIPPON OIL CO., LTD. (JP) 1997-12-23 US disclosed
EP-0551771-B1 Process for producing polysilanes NIPPON OIL CO LTD (JP) 1997-07-30 EP disclosed
US-5620531-A Photovoltaic element NIPPON OIL CO., LTD. (JP) 1997-04-15 US disclosed
EP-0717451-A2 Photovoltaic element NIPPON OIL CO., LTD. (JP) 1996-06-19 EP disclosed
EP-0630933-A2 A method of producing a semiconducting material NIPPON OIL CO. LTD. (JP) 1994-12-28 EP disclosed