Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL27458967 | 0.98 | MAPT (0.51) | MAPTTSHRPGRADRA2AADRA2B | |
| SCHEMBL5424308 | 0.84 | MAPT (0.50) | MAPTTSHRPGRADRA2AADRA2B | |
| SCHEMBL28050646 | 0.81 | CA1 (0.52) | MAPTTSHRTDP1KMT2AALDH1A1 | |
| SCHEMBL11428933 | 0.81 | KMT2A (0.54) | MAPTPGRADRA2AADRA2BHTR2A | |
| SCHEMBL21705085 | 0.81 | MAPT (0.47) | MAPTTSHRPGRADRA2AADRA2B | |
| SCHEMBL16513077 | 0.81 | MEN1 (0.60) | ADRA2BTDP1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL11428931 | 0.81 | KMT2A (0.54) | MAPTPGRADRA2AADRA2BHTR2A | |
| SCHEMBL27404124 | 0.81 | MAPT (0.47) | MAPTTSHRPGRADRA2AADRA2B | |
| SCHEMBL26712 | 0.80 | TSHR (0.52) | MAPTTSHRPGRADRA2AADRA2B | |
| SCHEMBL146504 | 0.80 | TSHR (0.52) | MAPTTSHRPGRADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114858944-B | Method for detecting p-methoxypropiophenone related substances | 石家庄四药有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-114858944-A | Method for detecting p-methoxypropiophenone related substances | 石家庄四药有限公司 | 2022-08-05 | — | — | CN | claimed |
| CN-110004162-B | Carbonyl reductase, gene and application of carbonyl reductase in methoxamine hydrochloride key intermediate | 长兴制药股份有限公司 | 2021-01-01 | — | — | CN | claimed |
| US-20240400784-A1 | Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition | LG CHEM, LTD. (KR) | 2024-12-05 | — | — | US | disclosed |
| CN-116217363-B | Method for continuously synthesizing 4-methoxy propiophenone | 江苏宏邦化工科技有限公司 | 2024-09-03 | — | — | CN | disclosed |
| US-12043724-B2 | Curable composition, film, laminated body, and display apparatus | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-07-23 | — | — | US | disclosed |
| US-20230367049-A1 | COLORED COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-11-16 | — | — | US | disclosed |
| US-20230348502-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-11-02 | — | — | US | disclosed |
| US-20230312869-A1 | COLORED RESIN COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-10-05 | — | — | US | disclosed |
| US-11766665-B2 | Method for efficiently synthesizing primary amines | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-09-26 | — | — | US | disclosed |
| WO-2023140047-A1 | COLORED COMPOSITION | 住友化学株式会社 | 2023-07-27 | — | — | WO | disclosed |
| WO-1993001158-A1 | METHOD FOR THE PREPARATION OF ARYLKETOAMINES | HOECHST CELANESE CORPORATION (US) | 1993-01-21 | — | — | WO | disclosed |
| EP-0115203-B1 | BENZHYDRYLPIPERAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1987-04-01 | — | — | EP | disclosed |
| EP-0048136-B1 | PROCESS FOR PREPARING ALPHA-AROMATIC GROUP SUBSTITUTED ALKANOIC ACIDS OR ESTERS THEREOF | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1986-06-11 | — | — | EP | disclosed |
| US-4504481-A | ENZYME INHIBITORS IN LIVER TO REDUCE TOXIC EFFECT OF DRUGS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1985-03-12 | — | — | US | disclosed |
| EP-0115203-A1 | Benzhydrylpiperazine derivatives, process for their preparation and pharmaceutical compositions containing them | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1984-08-08 | — | — | EP | disclosed |
| US-4225734-A | Process for producing symmetrical olefins | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1980-09-30 | — | — | US | disclosed |
| US-4142054-A | TRIVALENT THALLIUM SALT | THE UPJOHN COMPANY (US) | 1979-02-27 | — | — | US | disclosed |
| US-4135051-A | ENOL ETHER OF AN ARYL ALKYL KETONE WITH A THALLIJM SALT, REGENERATION OF THALLIUM SALT BY ADDING PERACID AND REACTIVE METAL COMPOUND | THE UPJOHN COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-4107439-A | Process for preparing arylalkanoic acid derivatives | THE UPJOHN COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348502-A1 | COMPOUND | GPX1, BAK1, GPX4 | MAPT 4062/4885TSHR 3833/4885PGR 4504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.