Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5424308 | 0.91 | MAPT (0.50) | MAPTPGRADRA2AADRA2BHTR2A | |
| SCHEMBL25419171 | 0.86 | LMNA (0.48) | MAPTPGRADRA2AADRA2BHTR2A | |
| SCHEMBL1155190 | 0.83 | PGR (0.47) | MAPTPGRADRA2AADRA2BHTR2A | |
| SCHEMBL27516060 | 0.82 | LMNA (0.48) | MAPTPGRADRA2AADRA2BHTR2A | |
| SCHEMBL17311056 | 0.81 | MAPT (0.43) | MAPTPGRADRA2AADRA2BHTR2A | |
| SCHEMBL2598221 | 0.81 | MAPT (0.53) | MAPTPGRADRA2AADRA2BHTR2A | |
| SCHEMBL11442931 | 0.80 | PGR (0.44) | MAPTPGRADRA2AADRA2BHTR2A | |
| SCHEMBL14944824 | 0.80 | CES2 (0.45) | MAPTKMT2AALDH1A1CYP3A4LMNA | |
| SCHEMBL11428931 | 0.79 | KMT2A (0.54) | MAPTPGRADRA2AADRA2BHTR2A | |
| SCHEMBL21705085 | 0.79 | MAPT (0.47) | MAPTPGRADRA2AADRA2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530241-A | Thioether substituted diphenyl pyrrolopyrrole diketone and preparation method and application thereof | 山东凯瑞尔光电科技有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-116969953-A | Diphenyl pyrrolo-pyrrole-dione derivative, pigment composition and application thereof | 山东凯瑞尔光电科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116693857-A | Compound containing multifunctional polysiloxane structure and application thereof | 烟台希尔德材料科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-1090617-C | Pyrrole derivatives and pharmaceutical compositions | NIPPON SHINYAKU CO LTD (JP) | 2002-09-11 | — | — | CN | disclosed |
| CN-1349796-A | Pyrrole derivatives and medicine composition | NIPPON SHINYAKU CO LTD (JP) | 2002-05-22 | — | — | CN | disclosed |
| CN-1186485-A | Pyrrole derivatives and pharmaceutical compositions | NIPPON SHINYAKU CO LTD (JP) | 1998-07-01 | — | — | CN | disclosed |