⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17991923 | 0.86 | LMNA (0.40) | — | |
| SCHEMBL7795070 | 0.69 | — | — | |
| SCHEMBL599023 | 0.69 | — | — | |
| SCHEMBL14463486 | 0.67 | — | — | |
| SCHEMBL9719073 | 0.67 | — | — | |
| SCHEMBL1828951 | 0.67 | — | — | |
| SCHEMBL22911698 | 0.65 | — | — | |
| 1,4-Butanediol SCHEMBL18642509 | 0.63 | SMN1; SMN2 (0.58) | — | |
| 1,3-Propanediol SCHEMBL4973361 | 0.63 | — | — | |
| 1,3-Propanediol SCHEMBL8850846 | 0.63 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082327-A4 | PERFLUORINATED ORGANO SUBSTITUTED CYCLOSILOXANES AND COPOLYMERS PREPARED FROM THESE CYCLOSILOXANES | CLARIANT LSM ITALIA SPA (US) | 2003-04-16 | — | — | EP | claimed |
| EP-1082327-A1 | PERFLUORINATED ORGANO SUBSTITUTED CYCLOSILOXANES AND COPOLYMERS PREPARED FROM THESE CYCLOSILOXANES | Archimica (Florida), Inc. (US) | 2001-03-14 | — | — | EP | claimed |
| WO-1999062916-A1 | PERFLUORINATED ORGANO SUBSTITUTED CYCLOSILOXANES AND COPOLYMERS PREPARED FROM THESE CYCLOSILOXANES | ARCHIMICA (FLORIDA) INC. (US) | 1999-12-09 | — | — | WO | claimed |
| US-5914420-A | UNSTRAINED POLYMERIZABLE CYCLOSILOXANES HAVING A SUBSTITUENT THAT CONTAINS A PERFLUORINATED ORGANIC MOIETY | PCR, INC. (US) | 1999-06-22 | — | — | US | claimed |
| US-5892086-A | Perfluorinated ether organo substituted cyclosiloxanes and copolymers prepared from these cyclosiloxanes | PCR, INC. (US) | 1999-04-06 | — | — | US | claimed |
| US-9068080-B2 | Merocyanine derivatives | BASF SE (DE) | 2015-06-30 | — | — | US | disclosed |
| US-8987493-B2 | Process for synthesis of silane dipeptide analogs | Temple University—Of the Commonwealth System of Higher Education (US) | 2015-03-24 | — | — | US | disclosed |
| US-8987493-B2 | Process for synthesis of silane dipeptide analogs | Temple University—Of the Commonwealth System of Higher Education (US) | 2015-03-24 | — | — | US | disclosed |
| US-20130096335-A1 | PROCESS FOR SYNTHESIS OF SILANE DIPEPTIDE ANALOGS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2013-04-18 | — | — | US | disclosed |
| US-20130096335-A1 | PROCESS FOR SYNTHESIS OF SILANE DIPEPTIDE ANALOGS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2013-04-18 | — | — | US | disclosed |
| WO-2011146842-A1 | PROCESS FOR SYNTHESIS OF SILANE DIPEPTIDE ANALOGS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2011-11-24 | — | — | WO | disclosed |
| WO-2011146842-A1 | PROCESS FOR SYNTHESIS OF SILANE DIPEPTIDE ANALOGS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2011-11-24 | — | — | WO | disclosed |
| US-5795947-A | RELEASE PAPER COATINGS | RHONE-POULENC CHIMIE (FR) | 1998-08-18 | — | — | US | disclosed |
| EP-0632085-A1 | Silicone polymers having olefinic functional groups, process for their preparation, and curable compositions comprising them | RHONE-POULENC CHIMIE (FR) | 1995-01-04 | — | — | EP | disclosed |