Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 3/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.52 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.44 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31212385 | 1.00 | KMO (0.55) | KMOCSNK2A2CSNK2BHPGDSKDM4E | |
| SCHEMBL25982803 | 0.87 | HPGDS (0.50) | KMOCSNK2A2CSNK2BHPGDSKDM4E | |
| SCHEMBL31212328 | 0.87 | HPGDS (0.50) | KMOCSNK2A2CSNK2BHPGDSKDM4E | |
| SCHEMBL31025344 | 0.85 | SMN1; SMN2 (0.58) | KMOCSNK2A2CSNK2BKDM4ENPC1 | |
| SCHEMBL4124819 | 0.85 | SMN1; SMN2 (0.58) | KMOCSNK2A2CSNK2BKDM4ENPC1 | |
| SCHEMBL25982799 | 0.84 | HPGDS (0.47) | KMOHPGDSKDM4ENPC1GAA | |
| SCHEMBL17942007 | 0.84 | BCL2L1 (0.53) | CSNK2A2CSNK2BKDM4ENPC1ALDH1A1 | |
| SCHEMBL31212211 | 0.84 | BCL2L1 (0.53) | CSNK2A2CSNK2BKDM4ENPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL400411 | 0.83 | SMN1; SMN2 (0.57) | KMOCSNK2A2CSNK2BKDM4ENPC1 | |
| SCHEMBL14758849 | 0.82 | KMO (0.56) | KMOKDM4ENPC1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150663-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | RETUNE PHARMA INC. (US) | 2023-08-10 | — | — | WO | disclosed |