Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23380370 | 0.84 | HTR2C (0.46) | HTR2CHTR2BKDM1ABRD4SLC6A2 | |
| SCHEMBL28003145 | 0.77 | KDM1A (0.46) | HTR2CHTR2BKDM1ASLC6A2SLC6A4 | |
| SCHEMBL28452283 | 0.77 | HTR2C (0.52) | HTR2CHTR2BHTR2APDE10A | |
| SCHEMBL29427088 | 0.77 | KDM1A (0.50) | HTR2CHTR2BKDM1ABRD4SLC6A2 | |
| SCHEMBL10046437 | 0.77 | KDM1A (0.50) | HTR2CHTR2BKDM1ABRD4SLC6A2 | |
| SCHEMBL23228754 | 0.74 | HTR2C (0.53) | HTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20380077 | 0.74 | CA1 (0.39) | CYP2C9F2PLGPLAUPLAT | |
| SCHEMBL21624161 | 0.73 | SLC6A4 (0.55) | HTR2CSLC6A4CYP2D6 | |
| SCHEMBL1794059 | 0.73 | ALDH1A1 (0.34) | ALDH1A1PDE10AF2PLGPLAU | |
| SCHEMBL23662637 | 0.73 | OPRL1 (0.34) | SLC6A2SLC6A4SLC6A3ALDH1A1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814331-B9 | NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY | ORSOBIO INC (US) | 2023-08-09 | — | — | EP | disclosed |