Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21315389 | 0.83 | POLB (0.36) | ALDH1A1MAPTMAPK1SMN1; SMN2GABRA1 | |
| SCHEMBL18365976 | 0.79 | KMT2A (0.45) | ALDH1A1MAPTMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL3798240 | 0.79 | PDE3B (0.39) | ALDH1A1MAPTMAPK1SMN1; SMN2GABRA1 | |
| SCHEMBL3801455 | 0.77 | ALDH1A1 (0.40) | ALDH1A1MAPTMAPK1SMN1; SMN2GABRA1 | |
| SCHEMBL19299945 | 0.76 | PDE4A (0.41) | ALDH1A1MAPTMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL19635706 | 0.75 | ALDH1A1 (0.39) | ALDH1A1MAPTMAPK1SMN1; SMN2GABRG2 | |
| SCHEMBL26969083 | 0.74 | ALDH1A1 (0.37) | ALDH1A1MAPTMAPK1SMN1; SMN2GABRA1 | |
| SCHEMBL21315230 | 0.73 | MAPT (0.34) | ALDH1A1MAPTMAPK1SMN1; SMN2GABRA1 | |
| SCHEMBL31737069 | 0.73 | MAPT (0.34) | ALDH1A1MAPTMAPK1SMN1; SMN2GABRA1 | |
| SCHEMBL29777592 | 0.73 | DRD3 (0.54) | ATMALDH1A1SMN1; SMN2NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725008-B2 | Ethanediamine-heterocycle derivatives as inhibitors of protein arginine methyltransferases | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725008-B2 | Ethanediamine-heterocycle derivatives as inhibitors of protein arginine methyltransferases | PRMT1, PRMT5, PRMT3 | ATM 421/4885ALDH1A1 1831/4885MAPT 3106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.