Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2598669 | 0.83 | ALDH1A1 (0.35) | ALDH1A1GAAHPGDKMT2AMEN1 | |
| SCHEMBL1119946 | 0.82 | GAA (0.45) | ALDH1A1GAAHPGDNPC1RAB9A | |
| SCHEMBL15961401 | 0.80 | RAB9A (0.46) | ALDH1A1GAAHPGDNPC1RAB9A | |
| SCHEMBL2598439 | 0.75 | MEN1 (0.38) | ALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL441577 | 0.74 | ALDH1A1 (0.44) | ALDH1A1GAAHPGDMAPTKDM4E | |
| SCHEMBL15961369 | 0.74 | NR1H2 (0.42) | ALDH1A1GAAHPGDNPC1RAB9A | |
| SCHEMBL18394638 | 0.73 | RAB9A (0.52) | ALDH1A1GAANPC1RAB9AKMT2A | |
| SCHEMBL441653 | 0.73 | ALDH1A1 (0.43) | ALDH1A1GAAHPGDKMT2AMAPT | |
| SCHEMBL15446675 | 0.73 | ALDH1A1 (0.43) | ALDH1A1GAAHPGDKMT2AHSD17B10 | |
| SCHEMBL31459287 | 0.72 | ALDH1A1 (0.44) | ALDH1A1GAAHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571873-B1 | BIS(DIFLUORMETHYL)PYRAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2015-06-24 | — | — | EP | disclosed |
| US-8815775-B2 | Bis(difluoromethyl)pyrazoles as fungicides | BAYER CROPSCIENCE AG (DE) | 2014-08-26 | — | — | US | disclosed |
| EP-2571873-A1 | BIS(DIFLUOROMETHYL) PYRAZOLES AS FUNGICIDES | Bayer CropScience AG (DE) | 2013-03-27 | — | — | EP | disclosed |
| US-20110301197-A1 | Bis(difluoromethyl)pyrazoles as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-12-08 | — | — | US | disclosed |
| WO-2011144586-A1 | BIS(DIFLUOROMETHYL) PYRAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301197-A1 | Bis(difluoromethyl)pyrazoles as Fungicides | CYP4X1, CYP1A1, CYP1B1 | ALDH1A1 1444/4885GAA 311/4885HPGD 3904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.