Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | HSPA8 | P11142 | 5/20 | 0.58 |
| ▸ | CDK2 | P24941 | 3/20 | 0.53 |
| ▸ | CDK1 | P06493 | 2/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.53 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.48 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141370 | 0.92 | HIF1A (0.81) | HIF1AHSPA8CDK2CDK1CCNA2 | |
| SCHEMBL25986492 | 0.90 | HIF1A (0.65) | HIF1AHSPA8CDK2CDK1CCNA2 | |
| SCHEMBL20141988 | 0.85 | HIF1A (0.77) | HIF1AHSPA8CDK2CDK1CCNA2 | |
| SCHEMBL22111053 | 0.85 | HIF1A (0.77) | HIF1AHSPA8CDK2CDK1CCNA2 | |
| SCHEMBL30131081 | 0.85 | HIF1A (0.77) | HIF1AHSPA8CDK2CDK1CCNA2 | |
| SCHEMBL23950000 | 0.83 | HIF1A (0.68) | HIF1AHSPA8CDK2CDK1CCNA2 | |
| SCHEMBL25986360 | 0.83 | HSPA8 (0.82) | HIF1AHSPA8CDK2CDK1CCNA2 | |
| SCHEMBL20141359 | 0.82 | HIF1A (0.75) | HIF1AHSPA8CDK2CDK1CCNA2 | |
| SCHEMBL12284814 | 0.82 | HIF1A (1.00) | HIF1AHSPA8CDK2CDK1CCNA2 | |
| SCHEMBL22111064 | 0.82 | HIF1A (0.81) | HIF1AHSPA8CDK2CDK1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233591-A1 | METHOD FOR TREATING POXVIRIDAE INFECTIONS | OYAGEN, INC. | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233591-A1 | METHOD FOR TREATING POXVIRIDAE INFECTIONS | ITPA, VAC14, MAVS | HIF1A 3831/4885HSPA8 1528/4885CDK2 2268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.