SCHEMBL25986916

SCHEMBL25986916

O=S(=O)(O)OCCSc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.52
MAPK1 P28482 1/20 0.52
FFAR1 O14842 1/20 0.44
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
RECQL P46063 1/20 0.42
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA13 Q8N1Q1 2/20 0.41
CA12 O43570 1/20 0.41
GAA P10253 1/20 0.41
USP2 O75604 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9647380 0.84 ALDH1A1 (0.56) ALDH1A1MAPK1FFAR1MTNR1AMTNR1B
SCHEMBL3444834 0.81 ALDH1A1 (0.51) ALDH1A1MAPK1CYP1A2CYP3A4CYP2C19
SCHEMBL5236263 0.81 ALDH1A1 (0.52) ALDH1A1MAPK1FFAR1MTNR1AMTNR1B
SCHEMBL8416274 0.77 ALDH1A1 (0.47) ALDH1A1MAPK1FFAR1MTNR1AMTNR1B
SCHEMBL6140666 0.74 ALDH1A1 (0.54) ALDH1A1MAPK1FFAR1MTNR1AMTNR1B
SCHEMBL11842736 0.73 ALDH1A1 (0.56) ALDH1A1MAPK1FFAR1MTNR1AMTNR1B
SCHEMBL3373578 0.72 CA1 (0.66) ALDH1A1MAPK1FFAR1CYP3A4NPC1
SCHEMBL9427645 0.72 ALDH1A1 (0.56) ALDH1A1MAPK1FFAR1MTNR1AMTNR1B
SCHEMBL16586149 0.72 ALDH1A1 (0.70) ALDH1A1MAPK1FFAR1MTNR1AMTNR1B
Sulfur Dioxide SCHEMBL27681092 0.72 CA2 (0.59) ALDH1A1MAPK1FFAR1CYP3A4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2861673-B1 METAL FREE REACTIVE DYES, PROCESS FOR THE PRODUCTION THEREOF AND THEIR USE DYSTAR COLOURS DISTRIB GMBH (DE) 2023-08-09 EP disclosed