Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083110 | 0.79 | ALOX5 (0.38) | ALOX5ALDH1A1LMNACYP3A4HSD11B1 | |
| SCHEMBL12354409 | 0.75 | POLB (0.37) | — | |
| SCHEMBL24483574 | 0.72 | — | — | |
| SCHEMBL12687982 | 0.72 | — | — | |
| SCHEMBL11208090 | 0.72 | ALOX5 (0.33) | ALOX5 | |
| SCHEMBL12346170 | 0.71 | ALOX5 (0.34) | ALOX5 | |
| SCHEMBL7511344 | 0.70 | ALOX5 (0.35) | ALOX5ALDH1A1LMNACYP3A4 | |
| SCHEMBL6280619 | 0.68 | ITGB3 (0.31) | ALOX5 | |
| SCHEMBL6280623 | 0.68 | ITGB3 (0.31) | ALOX5 | |
| SCHEMBL28419685 | 0.67 | FFAR3 (0.42) | FFAR3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571351-A1 | DIAZENIUMDIOLATE CYCLOHEXYL DERIVATIVES | Merck Sharp & Dohme Corp. (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011146371-A1 | DIAZENIUMDIOLATE CYCLOHEXYL DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2011-11-24 | — | — | WO | disclosed |