SCHEMBL25989152

SCHEMBL25989152

CN1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(CCO)C3=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 0.65
▸ MEN1 O00255 4/20 0.65
▸ KMT2A Q03164 4/20 0.65
▸ ALDH1A1 P00352 4/20 0.65
▸ NPC1 O15118 2/20 0.65
▸ RAB9A P51151 2/20 0.65
▸ HTT P42858 2/20 0.65
▸ RGS12 O14924 1/20 0.65
▸ LMNA P02545 1/20 0.65
▸ PABPC1 P11940 1/20 0.65
▸ RECQL P46063 1/20 0.65
▸ SMN1; SMN2 Q16637 1/20 0.65
▸ HEXA P06865 1/20 0.61
▸ HEXB P07686 1/20 0.61
▸ TERT O14746 7/20 0.55
▸ MAPT P10636 1/20 0.49
▸ AVPR1A P37288 1/20 0.49
▸ STAT3 P40763 1/20 0.46
▸ HIF1A Q16665 1/20 0.46
▸ PIN1 Q13526 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15712038 0.92 KDM4E (0.74) KDM4EMEN1KMT2AALDH1A1NPC1
SCHEMBL18470159 0.87 KDM4E (0.62) KDM4EMEN1KMT2AALDH1A1NPC1
SCHEMBL18470149 0.85 KDM4E (0.61) KDM4EMEN1KMT2AALDH1A1NPC1
SCHEMBL2744278 0.85 TERT (0.71) KDM4EMEN1KMT2AALDH1A1NPC1
SCHEMBL22746164 0.84 KDM4E (0.48) KDM4EMEN1KMT2AALDH1A1NPC1
SCHEMBL17775320 0.82 TERT (0.56) KDM4EMEN1KMT2AALDH1A1NPC1
SCHEMBL127059 0.81 MEN1 (0.55) KDM4EMEN1KMT2AALDH1A1NPC1
SCHEMBL30937815 0.81 MEN1 (0.55) KDM4EMEN1KMT2AALDH1A1NPC1
SCHEMBL16285017 0.81 ALDH1A1 (0.73) KDM4EMEN1KMT2AALDH1A1NPC1
SCHEMBL21477284 0.80 KDM4E (0.89) KDM4EMEN1KMT2AALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11789307-B2 Colorant filter, backlight unit, and liquid crystal display device FUJIFILM CORPORATION (JP) 2023-10-17 — — US disclosed
US-11733435-B2 Polarizing plate protective film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2023-08-22 — — US disclosed
Send feedback