Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.37 |
| ▸ | TUBB | P07437 | 2/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15757324 | 0.82 | ALDH1A1 (0.40) | CYP3A4ENPP2ALDH1A1CA1CA2 | |
| SCHEMBL2560197 | 0.80 | ALDH1A1 (0.53) | CYP3A4ALDH1A1CA1CA2MAPT | |
| SCHEMBL14121124 | 0.74 | TSHR (0.40) | CYP3A4ENPP2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9847949 | 0.74 | ALDH1A1 (0.46) | CYP3A4ALDH1A1CA1CA2TUBB1 | |
| SCHEMBL29807652 | 0.73 | ENPP2 (0.48) | ENPP2ALDH1A1CA1CA2TUBB4A | |
| SCHEMBL29469134 | 0.73 | ENPP2 (0.48) | ENPP2ALDH1A1CA1CA2TUBB4A | |
| SCHEMBL41499 | 0.73 | ENPP2 (0.48) | ENPP2ALDH1A1CA1CA2TUBB4A | |
| SCHEMBL41797 | 0.73 | ENPP2 (0.48) | ENPP2ALDH1A1CA1CA2TUBB4A | |
| SCHEMBL13696428 | 0.72 | ALDH1A1 (0.45) | CYP3A4ALDH1A1CA1CA2MAPT | |
| SCHEMBL19709408 | 0.72 | ALDH1A1 (0.43) | CYP3A4ALDH1A1CA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154962-A1 | CGAS INHIBITORS AND USES THEREOF | SINHA SUBHASH (US) | 2023-08-17 | — | — | WO | disclosed |