Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 1.00 |
| ▸ | PLAU | P00749 | 9/20 | 0.67 |
| ▸ | C1S | P09871 | 14/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14841090 | 1.00 | S100A4 (1.00) | S100A4PLAUC1SPLGPLAT | |
| SCHEMBL6926072 | 0.83 | S100A4 (0.71) | S100A4PLAUC1SPLGPLAT | |
| SCHEMBL6921044 | 0.80 | PLAU (1.00) | S100A4PLAUC1SPLGPLAT | |
| SCHEMBL6921283 | 0.69 | C1S (0.78) | PLAUC1SPLGPLATPRSS1 | |
| SCHEMBL6928432 | 0.67 | C1S (0.69) | S100A4PLAUC1SPLGPLAT | |
| SCHEMBL6919968 | 0.67 | C1S (0.73) | S100A4PLAUC1SPLGPLAT | |
| SCHEMBL6925416 | 0.67 | C1S (0.79) | PLAUC1SPLGPLATPRSS1 | |
| SCHEMBL7736128 | 0.67 | PLAU (0.70) | PLAUC1SPLGPLATPRSS1 | |
| SCHEMBL6921963 | 0.66 | C1S (0.70) | S100A4PLAUC1SPLGPLAT | |
| SCHEMBL6922269 | 0.66 | C1S (0.61) | S100A4PLAUC1SPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | claimed |
| WO-2011146101-A1 | CHEMICAL AGENTS FOR THE PREVENTION OR INHIBITION OF TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2011-11-24 | — | — | WO | claimed |
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | disclosed |
| WO-2011146101-A1 | CHEMICAL AGENTS FOR THE PREVENTION OR INHIBITION OF TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2011-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | S100A4, S100A6, S100A10 | S100A4 1/4885PLAU 1535/4885C1S 4238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.