Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 14/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 12/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 9/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.34 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935671 | 0.87 | PIK3CD (0.51) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL935884 | 0.87 | PIK3R1 (0.44) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL2599465 | 0.86 | PIK3CD (0.41) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL16671078 | 0.82 | PIK3CD (0.43) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL154563 | 0.80 | PIK3CD (0.58) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL154564 | 0.80 | PIK3CD (0.58) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL179598 | 0.80 | PIK3CD (0.58) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL935803 | 0.78 | PIK3R1 (0.46) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL9924638 | 0.78 | PIK3R1 (0.45) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 | |
| SCHEMBL935114 | 0.77 | PIK3CD (0.39) | PIK3CDPIK3CGPIK3CBPIK3CAPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571357-A1 | CHEMICAL COMPOUNDS, COMPOSITIONS AND METHODS FOR KINASE MODULATION | Intellikine, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011146882-A1 | CHEMICAL COMPOUNDS, COMPOSITIONS AND METHODS FOR KINASE MODULATION | INTELLIKINE, INC. (US) | 2011-11-24 | — | — | WO | disclosed |