Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 9/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 9/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25996349 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9ANPC1CYP1A2ALDH1A1 | |
| SCHEMBL25996347 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9ANPC1CYP1A2ALDH1A1 | |
| SCHEMBL25996308 | 0.90 | RAB9A (0.55) | SMN1; SMN2RAB9ANPC1CYP1A2ALDH1A1 | |
| SCHEMBL25996309 | 0.90 | RAB9A (0.55) | SMN1; SMN2RAB9ANPC1CYP1A2ALDH1A1 | |
| SCHEMBL25996310 | 0.90 | RAB9A (0.55) | SMN1; SMN2RAB9ANPC1CYP1A2ALDH1A1 | |
| SCHEMBL25355754 | 0.90 | RAB9A (0.44) | SMN1; SMN2RAB9ANPC1CYP1A2ALDH1A1 | |
| SCHEMBL25996527 | 0.90 | RAB9A (0.44) | SMN1; SMN2RAB9ANPC1CYP1A2ALDH1A1 | |
| SCHEMBL25994824 | 0.89 | NPBWR1 (0.45) | SMN1; SMN2RAB9ANPC1CYP1A2ALDH1A1 | |
| SCHEMBL25359920 | 0.88 | CA12 (0.43) | SMN1; SMN2RAB9ANPC1CYP1A2ALDH1A1 | |
| SCHEMBL25996525 | 0.88 | CA12 (0.43) | SMN1; SMN2RAB9ANPC1CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |